Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)

 Full screen view
Filter results: >>>>
Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC38 Dactolisib 2 72
3.2
 611.5 3001.5 690.5
0.505
 -0.056 0.204 2.120
HCC38 BEZ235 0 2 72
HCC38 Buparlisib 2 72
0.001
 3132.8 3048.5 690.5
-3.0
 1.030 1.030 2.142
HCC38 BKM120 0 2 72
HCC38 Buparlisib 2 72
0.0032
 3145.3 3048.5 690.5
-2.49
 1.030 1.030 2.142
HCC38 BKM120 0 2 72
HCC38 Buparlisib 2 72
0.01
 3212.0 3048.5 690.5
-2.0
 1.050 1.050 2.142
HCC38 BKM120 0 2 72
HCC38 Buparlisib 2 72
0.032
 3141.0 3048.5 690.5
-1.49
 1.030 1.030 2.142
HCC38 BKM120 0 2 72
HCC38 Buparlisib 2 72
0.1
 2958.8 3048.5 690.5
-1.0
 0.972 0.971 2.142
HCC38 BKM120 0 2 72
HCC38 Buparlisib 2 72
0.32
 2663.3 3048.5 690.5
-0.495
 0.878 0.874 2.142
HCC38 BKM120 0 2 72
HCC38 Buparlisib 2 72
1.0
 1471.0 3048.5 690.5
0.0
 0.423 0.483 2.142
HCC38 BKM120 0 2 72
HCC38 Buparlisib 2 72
3.2
 445.0 3048.5 690.5
0.505
 -0.185 0.146 2.142
HCC38 BKM120 0 2 72
HCC38 BX-912 2 72
0.001
 3135.3 3142.0 690.5
-3.0
 0.998 0.998 2.186
HCC38 BX912 0 2 72
HCC38 BX-912 2 72
0.0032
 3185.3 3142.0 690.5
-2.49
 1.010 1.010 2.186
HCC38 BX912 0 2 72
HCC38 BX-912 2 72
0.01
 3099.8 3142.0 690.5
-2.0
 0.988 0.987 2.186
HCC38 BX912 0 2 72
HCC38 BX-912 2 72
0.032
 3186.0 3142.0 690.5
-1.49
 1.010 1.010 2.186
HCC38 BX912 0 2 72
HCC38 BX-912 2 72
0.1
 3012.0 3142.0 690.5
-1.0
 0.962 0.959 2.186
HCC38 BX912 0 2 72
HCC38 BX-912 2 72
0.32
 2847.8 3142.0 690.5
-0.495
 0.912 0.906 2.186
HCC38 BX912 0 2 72
HCC38 BX-912 2 72
1.0
 658.8 3142.0 690.5
0.0
 -0.021 0.210 2.186
HCC38 BX912 0 2 72
HCC38 BX-912 2 72
3.2
 390.8 3142.0 690.5
0.505
 -0.229 0.124 2.186
HCC38 BX912 0 2 72
HCC38 Alpelisib 2 72
0.001
 2453.5 2931.8 690.5
-3.0
 0.836 0.837 2.086
HCC38 BYL719 0 2 72
HCC38 Alpelisib 2 72
0.0032
 2449.5 2931.8 690.5
-2.49
 0.835 0.836 2.086
HCC38 BYL719 0 2 72
HCC38 Alpelisib 2 72
0.01
 3033.5 2931.8 690.5
-2.0
 1.030 1.030 2.086
HCC38 BYL719 0 2 72
HCC38 Alpelisib 2 72
0.032
 2779.0 2931.8 690.5
-1.49
 0.949 0.948 2.086
HCC38 BYL719 0 2 72
HCC38 Alpelisib 2 72
0.1
 3033.8 2931.8 690.5
-1.0
 1.030 1.030 2.086
HCC38 BYL719 0 2 72
HCC38 Alpelisib 2 72
0.32
 2794.3 2931.8 690.5
-0.495
 0.954 0.953 2.086
HCC38 BYL719 0 2 72
HCC38 Alpelisib 2 72
1.0
 2818.5 2931.8 690.5
0.0
 0.963 0.961 2.086
HCC38 BYL719 0 2 72
HCC38 Alpelisib 2 72
3.2
 2486.3 2931.8 690.5
0.505
 0.848 0.848 2.086
HCC38 BYL719 0 2 72