LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Trametinib | 180622_MC_15 | 7238 | 0.0227 | 76 | 90 | 13 | 14 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_5 | 166 | 0.0224 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00165 | 0.5572 |
| Trametinib | 180622_MC_15 | 7787 | 0.0175 | 46 | 91 | 13 | 21 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_6 | 137 | 0.0173 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00678 | 0.5862 |
| Trametinib | 180622_MC_16 | 8459 | 0.0269 | 89 | 141 | 6 | 21 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_7 | 230 | 0.0265 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00240 | 0.6197 |
| Trametinib | 180622_MC_16 | 7202 | 0.0194 | 69 | 72 | 10 | 9 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 141 | 0.0192 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00487 | 0.5553 |
| Trametinib | 180622_MC_16 | 8065 | 0.0199 | 83 | 79 | 14 | 12 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 162 | 0.0197 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00438 | 0.6003 |
| Trametinib | 180622_MC_14 | 3298 | 0.0327 | 64 | 46 | 3 | 15 | Trametinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 110 | 0.0323 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00821 | 0.2770 |
| Trametinib | 180622_MC_14 | 2860 | 0.0322 | 62 | 32 | 14 | 7 | Trametinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_2 | 94 | 0.0318 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00775 | 0.2319 |
| Trametinib | 180622_MC_14 | 3021 | 0.0301 | 68 | 25 | 14 | 8 | Trametinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_3 | 93 | 0.0299 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00580 | 0.2490 |
| Trametinib | 180622_MC_15 | 3304 | 0.0414 | 99 | 42 | 9 | 13 | Trametinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_4 | 141 | 0.0409 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01686 | 0.2776 |
| Trametinib | 180622_MC_15 | 3105 | 0.0373 | 83 | 36 | 12 | 3 | Trametinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_5 | 119 | 0.0369 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01284 | 0.2577 |
| Trametinib | 180622_MC_15 | 3270 | 0.0369 | 90 | 34 | 14 | 8 | Trametinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_6 | 124 | 0.0365 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01247 | 0.2742 |
| Trametinib | 180622_MC_16 | 3555 | 0.0521 | 127 | 65 | 3 | 21 | Trametinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 192 | 0.0512 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02717 | 0.3014 |
| Trametinib | 180622_MC_16 | 3380 | 0.0697 | 137 | 108 | 5 | 4 | Trametinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 245 | 0.0676 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04352 | 0.2849 |
| Trametinib | 180622_MC_16 | 3399 | 0.0438 | 97 | 56 | 7 | 22 | Trametinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 153 | 0.0431 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01901 | 0.2867 |
| Trametinib | 180622_MC_14 | 2014 | 0.0456 | 49 | 45 | 6 | 4 | Trametinib | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_1 | 94 | 0.0446 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02052 | 0.1275 |
| Trametinib | 180622_MC_14 | 2566 | 0.0375 | 50 | 48 | 7 | 12 | Trametinib | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_2 | 98 | 0.0368 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01272 | 0.1986 |
| Trametinib | 180622_MC_14 | 2375 | 0.0433 | 71 | 35 | 14 | 14 | Trametinib | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_3 | 106 | 0.0427 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01866 | 0.1754 |
| Trametinib | 180622_MC_15 | 2610 | 0.0553 | 85 | 64 | 7 | 4 | Trametinib | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_4 | 149 | 0.0540 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02994 | 0.2037 |
| Trametinib | 180622_MC_15 | 2390 | 0.0402 | 50 | 48 | 13 | 16 | Trametinib | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_5 | 98 | 0.0394 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01532 | 0.1773 |
| Trametinib | 180622_MC_15 | 2331 | 0.0469 | 77 | 36 | 14 | 12 | Trametinib | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_6 | 113 | 0.0462 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02217 | 0.1699 |
| Trametinib | 180622_MC_16 | 2183 | 0.1093 | 140 | 114 | 9 | 5 | Trametinib | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_7 | 254 | 0.1042 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.08016 | 0.1507 |
| Trametinib | 180622_MC_16 | 2299 | 0.0615 | 108 | 40 | 10 | 5 | Trametinib | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_8 | 148 | 0.0605 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03641 | 0.1658 |
| Trametinib | 180622_MC_16 | 2425 | 0.0693 | 116 | 60 | 11 | 10 | Trametinib | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_9 | 176 | 0.0677 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04360 | 0.1816 |
| Trametinib | 180622_MC_14 | 2455 | 0.0590 | 103 | 48 | 4 | 17 | Trametinib | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_1 | 151 | 0.0579 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03388 | 0.1853 |
| Trametinib | 180622_MC_14 | 2356 | 0.0577 | 86 | 55 | 8 | 13 | Trametinib | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_2 | 141 | 0.0565 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03240 | 0.1730 |