LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dasatinib | 180622_MC_16 | 4676 | 0.0873 | 103 | 314 | 8 | 19 | Dasatinib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_7 | 417 | 0.0819 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05781 | 0.3946 |
| Dasatinib | 180622_MC_16 | 4172 | 0.1185 | 164 | 350 | 9 | 4 | Dasatinib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_8 | 514 | 0.1097 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.08562 | 0.3550 |
| Dasatinib | 180622_MC_16 | 5267 | 0.0791 | 90 | 334 | 12 | 11 | Dasatinib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_9 | 424 | 0.0745 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05044 | 0.4372 |
| Dasatinib | 180622_MC_14 | 1620 | 0.3190 | 54 | 480 | 7 | 20 | Dasatinib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_1 | 534 | 0.2479 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.22384 | 0.0672 |
| Dasatinib | 180622_MC_14 | 1552 | 0.2843 | 80 | 384 | 12 | 3 | Dasatinib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_2 | 464 | 0.2302 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.20609 | 0.0557 |
| Dasatinib | 180622_MC_14 | 1743 | 0.2744 | 68 | 429 | 13 | 9 | Dasatinib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_3 | 497 | 0.2219 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.19781 | 0.0871 |
| Dasatinib | 180622_MC_15 | 2165 | 0.2346 | 90 | 439 | 12 | 8 | Dasatinib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_4 | 529 | 0.1964 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.17229 | 0.1483 |
| Dasatinib | 180622_MC_15 | 2271 | 0.1789 | 60 | 357 | 13 | 20 | Dasatinib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_5 | 417 | 0.1551 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.13107 | 0.1622 |
| Dasatinib | 180622_MC_15 | 2283 | 0.1730 | 70 | 337 | 13 | 22 | Dasatinib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_6 | 407 | 0.1513 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.12723 | 0.1637 |
| Dasatinib | 180622_MC_16 | 2213 | 0.1502 | 137 | 216 | 3 | 13 | Dasatinib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_7 | 353 | 0.1376 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.11350 | 0.1546 |
| Dasatinib | 180622_MC_16 | 2605 | 0.1556 | 113 | 310 | 4 | 11 | Dasatinib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_8 | 423 | 0.1397 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.11563 | 0.2032 |
| Dasatinib | 180622_MC_16 | 2125 | 0.1830 | 115 | 295 | 11 | 11 | Dasatinib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_9 | 410 | 0.1617 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.13767 | 0.1429 |
| Dasatinib | 180622_MC_14 | 773 | 0.7206 | 204 | 500 | 4 | 13 | Dasatinib | 9.98 | treatment | 72 | 3 | MCF10A-GM_1 | 704 | 0.4766 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.45257 | -0.1146 |
| Dasatinib | 180622_MC_14 | 662 | 0.7597 | 137 | 470 | 7 | 11 | Dasatinib | 9.98 | treatment | 72 | 3 | MCF10A-GM_2 | 607 | 0.4783 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.45426 | -0.1486 |
| Dasatinib | 180622_MC_14 | 688 | 0.8005 | 139 | 523 | 8 | 19 | Dasatinib | 9.98 | treatment | 72 | 3 | MCF10A-GM_3 | 662 | 0.4904 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.46630 | -0.1403 |
| Dasatinib | 180622_MC_15 | 865 | 0.6392 | 144 | 501 | 6 | 4 | Dasatinib | 9.98 | treatment | 72 | 3 | MCF10A-GM_4 | 645 | 0.4272 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.40308 | -0.0891 |
| Dasatinib | 180622_MC_15 | 679 | 0.7844 | 216 | 486 | 7 | 19 | Dasatinib | 9.98 | treatment | 72 | 3 | MCF10A-GM_5 | 702 | 0.5083 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.48426 | -0.1431 |
| Dasatinib | 180622_MC_15 | 825 | 0.6396 | 149 | 474 | 12 | 19 | Dasatinib | 9.98 | treatment | 72 | 3 | MCF10A-GM_6 | 623 | 0.4302 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.40618 | -0.0999 |
| Dasatinib | 180622_MC_16 | 831 | 0.7577 | 238 | 572 | 5 | 8 | Dasatinib | 9.98 | treatment | 72 | 3 | MCF10A-GM_7 | 810 | 0.4936 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.46953 | -0.0983 |
| Dasatinib | 180622_MC_16 | 900 | 0.6079 | 189 | 473 | 7 | 16 | Dasatinib | 9.98 | treatment | 72 | 3 | MCF10A-GM_8 | 662 | 0.4238 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.39975 | -0.0800 |
| Dasatinib | 180622_MC_16 | 893 | 0.5814 | 158 | 453 | 11 | 16 | Dasatinib | 9.98 | treatment | 72 | 3 | MCF10A-GM_9 | 611 | 0.4063 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.38218 | -0.0818 |
| Etoposide | 180622_MC_14 | 19547 | 0.0279 | 64 | 484 | 4 | 7 | Etoposide | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 548 | 0.0273 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00320 | 1.0011 |
| Etoposide | 180622_MC_14 | 19360 | 0.0233 | 41 | 412 | 5 | 10 | Etoposide | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 453 | 0.0229 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00120 | 0.9962 |
| Etoposide | 180622_MC_14 | 18783 | 0.0221 | 44 | 372 | 12 | 10 | Etoposide | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_3 | 416 | 0.0217 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00240 | 0.9810 |
| Etoposide | 180622_MC_15 | 18220 | 0.0226 | 87 | 326 | 10 | 3 | Etoposide | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_4 | 413 | 0.0222 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00190 | 0.9659 |