LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Trametinib | 180622_MC_14 | 2335 | 0.0500 | 66 | 54 | 11 | 10 | Trametinib | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_3 | 120 | 0.0489 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02481 | 0.1704 |
| Trametinib | 180622_MC_15 | 2500 | 0.0520 | 77 | 57 | 4 | 22 | Trametinib | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_4 | 134 | 0.0509 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02681 | 0.1907 |
| Trametinib | 180622_MC_15 | 2460 | 0.0674 | 106 | 67 | 8 | 12 | Trametinib | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_5 | 173 | 0.0657 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04164 | 0.1859 |
| Trametinib | 180622_MC_15 | 2449 | 0.0590 | 92 | 58 | 14 | 7 | Trametinib | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_6 | 150 | 0.0577 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03365 | 0.1845 |
| Trametinib | 180622_MC_16 | 2371 | 0.0734 | 122 | 61 | 6 | 13 | Trametinib | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_7 | 183 | 0.0717 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04758 | 0.1749 |
| Trametinib | 180622_MC_16 | 2322 | 0.0770 | 120 | 68 | 8 | 9 | Trametinib | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_8 | 188 | 0.0749 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05083 | 0.1687 |
| Trametinib | 180622_MC_16 | 2247 | 0.0777 | 120 | 64 | 10 | 21 | Trametinib | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_9 | 184 | 0.0757 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05162 | 0.1591 |
| Trametinib | 180622_MC_14 | 2181 | 0.0649 | 67 | 79 | 3 | 20 | Trametinib | 0.319359801 | treatment | 72 | 3 | MCF10A-GM_1 | 146 | 0.0627 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03867 | 0.1504 |
| Trametinib | 180622_MC_14 | 2335 | 0.0616 | 84 | 65 | 4 | 3 | Trametinib | 0.319359801 | treatment | 72 | 3 | MCF10A-GM_2 | 149 | 0.0600 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03592 | 0.1704 |
| Trametinib | 180622_MC_14 | 2215 | 0.0770 | 109 | 70 | 8 | 5 | Trametinib | 0.319359801 | treatment | 72 | 3 | MCF10A-GM_3 | 179 | 0.0748 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05070 | 0.1549 |
| Trametinib | 180622_MC_15 | 2426 | 0.0548 | 58 | 78 | 6 | 22 | Trametinib | 0.319359801 | treatment | 72 | 3 | MCF10A-GM_4 | 136 | 0.0531 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02902 | 0.1817 |
| Trametinib | 180622_MC_15 | 2565 | 0.0560 | 95 | 54 | 7 | 10 | Trametinib | 0.319359801 | treatment | 72 | 3 | MCF10A-GM_5 | 149 | 0.0549 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03083 | 0.1985 |
| Trametinib | 180622_MC_15 | 2224 | 0.0528 | 85 | 37 | 10 | 19 | Trametinib | 0.319359801 | treatment | 72 | 3 | MCF10A-GM_6 | 122 | 0.0520 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02794 | 0.1561 |
| Trametinib | 180622_MC_16 | 2251 | 0.0552 | 85 | 44 | 8 | 3 | Trametinib | 0.319359801 | treatment | 72 | 3 | MCF10A-GM_7 | 129 | 0.0542 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03013 | 0.1596 |
| Trametinib | 180622_MC_16 | 2234 | 0.0959 | 143 | 85 | 8 | 13 | Trametinib | 0.319359801 | treatment | 72 | 3 | MCF10A-GM_8 | 228 | 0.0926 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.06854 | 0.1574 |
| Trametinib | 180622_MC_16 | 2427 | 0.0875 | 166 | 61 | 11 | 8 | Trametinib | 0.319359801 | treatment | 72 | 3 | MCF10A-GM_9 | 227 | 0.0855 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.06146 | 0.1819 |
| Trametinib | 180622_MC_14 | 2307 | 0.0589 | 70 | 70 | 8 | 16 | Trametinib | 0.998 | treatment | 72 | 3 | MCF10A-GM_1 | 140 | 0.0572 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03315 | 0.1668 |
| Trametinib | 180622_MC_14 | 2341 | 0.0543 | 92 | 40 | 9 | 11 | Trametinib | 0.998 | treatment | 72 | 3 | MCF10A-GM_2 | 132 | 0.0534 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02931 | 0.1711 |
| Trametinib | 180622_MC_14 | 2190 | 0.0542 | 62 | 60 | 9 | 21 | Trametinib | 0.998 | treatment | 72 | 3 | MCF10A-GM_3 | 122 | 0.0528 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02870 | 0.1516 |
| Trametinib | 180622_MC_15 | 2224 | 0.0588 | 89 | 47 | 8 | 10 | Trametinib | 0.998 | treatment | 72 | 3 | MCF10A-GM_4 | 136 | 0.0576 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03356 | 0.1561 |
| Trametinib | 180622_MC_15 | 2297 | 0.0600 | 85 | 58 | 8 | 21 | Trametinib | 0.998 | treatment | 72 | 3 | MCF10A-GM_5 | 143 | 0.0586 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03454 | 0.1655 |
| Trametinib | 180622_MC_15 | 2316 | 0.0614 | 78 | 69 | 9 | 22 | Trametinib | 0.998 | treatment | 72 | 3 | MCF10A-GM_6 | 147 | 0.0597 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03562 | 0.1680 |
| Trametinib | 180622_MC_16 | 2448 | 0.0778 | 134 | 67 | 6 | 20 | Trametinib | 0.998 | treatment | 72 | 3 | MCF10A-GM_7 | 201 | 0.0759 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05181 | 0.1844 |
| Trametinib | 180622_MC_16 | 2130 | 0.0847 | 102 | 87 | 13 | 4 | Trametinib | 0.998 | treatment | 72 | 3 | MCF10A-GM_8 | 189 | 0.0815 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05743 | 0.1435 |
| Trametinib | 180622_MC_16 | 2306 | 0.0608 | 80 | 65 | 14 | 7 | Trametinib | 0.998 | treatment | 72 | 3 | MCF10A-GM_9 | 145 | 0.0592 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03509 | 0.1667 |