LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Taxol | 180622_MC_16 | 493 | 1.0083 | 474 | 501 | 7 | 21 | Paclitaxel | 0.312706472 | treatment | 72 | 3 | MCF10A-GM_7 | 975 | 0.6642 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.64010 | -0.2096 |
| Taxol | 180622_MC_16 | 388 | 1.0496 | 257 | 420 | 10 | 22 | Paclitaxel | 0.312706472 | treatment | 72 | 3 | MCF10A-GM_8 | 677 | 0.6357 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.61161 | -0.2560 |
| Taxol | 180622_MC_16 | 413 | 0.9814 | 286 | 400 | 14 | 15 | Paclitaxel | 0.312706472 | treatment | 72 | 3 | MCF10A-GM_9 | 686 | 0.6242 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.60014 | -0.2442 |
| Trametinib | 180622_MC_14 | 16655 | 0.0201 | 59 | 277 | 9 | 20 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_1 | 336 | 0.0198 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00429 | 0.9218 |
| Trametinib | 180622_MC_14 | 16791 | 0.0158 | 58 | 209 | 10 | 4 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_2 | 267 | 0.0157 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00842 | 0.9258 |
| Trametinib | 180622_MC_14 | 17040 | 0.0168 | 35 | 252 | 11 | 11 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_3 | 287 | 0.0166 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00750 | 0.9329 |
| Trametinib | 180622_MC_15 | 16958 | 0.0198 | 62 | 275 | 3 | 19 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_4 | 337 | 0.0195 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00458 | 0.9306 |
| Trametinib | 180622_MC_15 | 16502 | 0.0214 | 73 | 282 | 4 | 17 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_5 | 355 | 0.0211 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00301 | 0.9173 |
| Trametinib | 180622_MC_15 | 17565 | 0.0189 | 52 | 281 | 14 | 19 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_6 | 333 | 0.0186 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00546 | 0.9478 |
| Trametinib | 180622_MC_16 | 17410 | 0.0179 | 94 | 219 | 5 | 16 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_7 | 313 | 0.0177 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00641 | 0.9434 |
| Trametinib | 180622_MC_16 | 17043 | 0.0232 | 120 | 279 | 7 | 11 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_8 | 399 | 0.0229 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00119 | 0.9330 |
| Trametinib | 180622_MC_16 | 17251 | 0.0220 | 74 | 308 | 12 | 19 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_9 | 382 | 0.0217 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00240 | 0.9390 |
| Trametinib | 180622_MC_14 | 13225 | 0.0185 | 50 | 196 | 6 | 8 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_1 | 246 | 0.0183 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00581 | 0.8131 |
| Trametinib | 180622_MC_14 | 12864 | 0.0200 | 57 | 202 | 10 | 19 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_2 | 259 | 0.0197 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00433 | 0.8005 |
| Trametinib | 180622_MC_14 | 12603 | 0.0203 | 61 | 196 | 14 | 21 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_3 | 257 | 0.0200 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00408 | 0.7912 |
| Trametinib | 180622_MC_15 | 12817 | 0.0212 | 82 | 192 | 5 | 5 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_4 | 274 | 0.0209 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00314 | 0.7989 |
| Trametinib | 180622_MC_15 | 13705 | 0.0198 | 91 | 182 | 7 | 15 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_5 | 273 | 0.0195 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00454 | 0.8295 |
| Trametinib | 180622_MC_15 | 13100 | 0.0200 | 87 | 177 | 7 | 21 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_6 | 264 | 0.0198 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00431 | 0.8088 |
| Trametinib | 180622_MC_16 | 13959 | 0.0232 | 72 | 254 | 4 | 18 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_7 | 326 | 0.0228 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00125 | 0.8380 |
| Trametinib | 180622_MC_16 | 14025 | 0.0235 | 132 | 200 | 9 | 19 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_8 | 332 | 0.0231 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00094 | 0.8402 |
| Trametinib | 180622_MC_16 | 13391 | 0.0184 | 96 | 152 | 12 | 14 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_9 | 248 | 0.0182 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00588 | 0.8189 |
| Trametinib | 180622_MC_14 | 6791 | 0.0363 | 94 | 156 | 4 | 11 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 250 | 0.0355 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01144 | 0.5324 |
| Trametinib | 180622_MC_14 | 6095 | 0.0251 | 72 | 83 | 12 | 21 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 155 | 0.0248 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00073 | 0.4911 |
| Trametinib | 180622_MC_14 | 6559 | 0.0158 | 27 | 77 | 13 | 18 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_3 | 104 | 0.0156 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00846 | 0.5190 |
| Trametinib | 180622_MC_15 | 6953 | 0.0291 | 100 | 105 | 7 | 3 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_4 | 205 | 0.0286 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00457 | 0.5415 |