LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Etoposide | 180622_MC_14 | 1318 | 0.0821 | 83 | 32 | 3 | 4 | Etoposide | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_1 | 115 | 0.0803 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05618 | 0.0130 |
| Etoposide | 180622_MC_14 | 1513 | 0.0926 | 107 | 43 | 4 | 19 | Etoposide | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_2 | 150 | 0.0902 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.06613 | 0.0490 |
| Etoposide | 180622_MC_14 | 1393 | 0.0585 | 61 | 24 | 8 | 20 | Etoposide | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_3 | 85 | 0.0575 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03344 | 0.0273 |
| Etoposide | 180622_MC_15 | 1391 | 0.0767 | 96 | 18 | 6 | 8 | Etoposide | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_4 | 114 | 0.0757 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05168 | 0.0269 |
| Etoposide | 180622_MC_15 | 1395 | 0.0783 | 86 | 30 | 14 | 4 | Etoposide | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_5 | 116 | 0.0768 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05270 | 0.0277 |
| Etoposide | 180622_MC_15 | 1379 | 0.0657 | 67 | 28 | 14 | 17 | Etoposide | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_6 | 95 | 0.0645 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04038 | 0.0247 |
| Etoposide | 180622_MC_16 | 1387 | 0.0817 | 94 | 27 | 4 | 3 | Etoposide | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_7 | 121 | 0.0802 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05617 | 0.0262 |
| Etoposide | 180622_MC_16 | 1383 | 0.1182 | 140 | 40 | 8 | 10 | Etoposide | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_8 | 180 | 0.1152 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.09110 | 0.0254 |
| Etoposide | 180622_MC_16 | 1357 | 0.0821 | 92 | 27 | 12 | 4 | Etoposide | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_9 | 119 | 0.0806 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05656 | 0.0205 |
| Etoposide | 180622_MC_14 | 1341 | 0.0908 | 91 | 39 | 4 | 15 | Etoposide | 9.98 | treatment | 72 | 3 | MCF10A-GM_1 | 130 | 0.0884 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.06431 | 0.0175 |
| Etoposide | 180622_MC_14 | 1284 | 0.0854 | 75 | 41 | 6 | 22 | Etoposide | 9.98 | treatment | 72 | 3 | MCF10A-GM_2 | 116 | 0.0829 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05879 | 0.0064 |
| Etoposide | 180622_MC_14 | 1322 | 0.1163 | 114 | 53 | 10 | 7 | Etoposide | 9.98 | treatment | 72 | 3 | MCF10A-GM_3 | 167 | 0.1122 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.08809 | 0.0138 |
| Etoposide | 180622_MC_15 | 1439 | 0.0724 | 80 | 30 | 4 | 13 | Etoposide | 9.98 | treatment | 72 | 3 | MCF10A-GM_4 | 110 | 0.0710 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04695 | 0.0358 |
| Etoposide | 180622_MC_15 | 1457 | 0.1289 | 172 | 38 | 7 | 17 | Etoposide | 9.98 | treatment | 72 | 3 | MCF10A-GM_5 | 210 | 0.1260 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.10191 | 0.0390 |
| Etoposide | 180622_MC_15 | 1428 | 0.0805 | 100 | 23 | 14 | 16 | Etoposide | 9.98 | treatment | 72 | 3 | MCF10A-GM_6 | 123 | 0.0793 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05524 | 0.0338 |
| Etoposide | 180622_MC_16 | 1349 | 0.1384 | 147 | 60 | 9 | 8 | Etoposide | 9.98 | treatment | 72 | 3 | MCF10A-GM_7 | 207 | 0.1330 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.10897 | 0.0190 |
| Etoposide | 180622_MC_16 | 1308 | 0.1736 | 167 | 89 | 13 | 7 | Etoposide | 9.98 | treatment | 72 | 3 | MCF10A-GM_8 | 256 | 0.1637 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.13962 | 0.0111 |
| Etoposide | 180622_MC_16 | 1383 | 0.0987 | 107 | 40 | 13 | 12 | Etoposide | 9.98 | treatment | 72 | 3 | MCF10A-GM_9 | 147 | 0.0961 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.07201 | 0.0254 |
| Neratinib | 180622_MC_14 | 19274 | 0.0227 | 52 | 387 | 3 | 13 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_1 | 439 | 0.0223 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00180 | 0.9940 |
| Neratinib | 180622_MC_14 | 19813 | 0.0276 | 76 | 473 | 8 | 22 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_2 | 549 | 0.0270 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00289 | 1.0079 |
| Neratinib | 180622_MC_14 | 19076 | 0.0225 | 48 | 383 | 11 | 17 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_3 | 431 | 0.0221 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00197 | 0.9888 |
| Neratinib | 180622_MC_15 | 19782 | 0.0233 | 55 | 408 | 3 | 17 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_4 | 463 | 0.0229 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00120 | 1.0071 |
| Neratinib | 180622_MC_15 | 19634 | 0.0204 | 63 | 339 | 14 | 10 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_5 | 402 | 0.0201 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00400 | 1.0033 |
| Neratinib | 180622_MC_15 | 19783 | 0.0196 | 53 | 335 | 14 | 11 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_6 | 388 | 0.0192 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00483 | 1.0072 |
| Neratinib | 180622_MC_16 | 19771 | 0.0249 | 73 | 422 | 4 | 5 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_7 | 495 | 0.0244 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00036 | 1.0068 |