LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180622_MC_16 | 19479 | 0.0238 | 95 | 371 | 11 | 22 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_8 | 466 | 0.0234 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00070 | 0.9993 |
| Neratinib | 180622_MC_16 | 19672 | 0.0239 | 77 | 395 | 13 | 16 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_9 | 472 | 0.0234 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00064 | 1.0043 |
| Neratinib | 180622_MC_14 | 19375 | 0.0232 | 55 | 396 | 5 | 15 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 451 | 0.0227 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00132 | 0.9966 |
| Neratinib | 180622_MC_14 | 19641 | 0.0246 | 43 | 442 | 9 | 8 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 485 | 0.0241 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00003 | 1.0035 |
| Neratinib | 180622_MC_14 | 18911 | 0.0230 | 56 | 380 | 13 | 12 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_3 | 436 | 0.0225 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00153 | 0.9844 |
| Neratinib | 180622_MC_15 | 19547 | 0.0243 | 56 | 420 | 4 | 21 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_4 | 476 | 0.0238 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00030 | 1.0011 |
| Neratinib | 180622_MC_15 | 18782 | 0.0199 | 55 | 319 | 8 | 16 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_5 | 374 | 0.0195 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00454 | 0.9810 |
| Neratinib | 180622_MC_15 | 18971 | 0.0175 | 52 | 280 | 11 | 4 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_6 | 332 | 0.0172 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00687 | 0.9860 |
| Neratinib | 180622_MC_16 | 20017 | 0.0324 | 65 | 586 | 4 | 7 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_7 | 651 | 0.0315 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00743 | 1.0131 |
| Neratinib | 180622_MC_16 | 19339 | 0.0236 | 90 | 368 | 4 | 16 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 458 | 0.0231 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00093 | 0.9957 |
| Neratinib | 180622_MC_16 | 19865 | 0.0251 | 69 | 432 | 6 | 7 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 501 | 0.0246 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00053 | 1.0093 |
| Neratinib | 180622_MC_14 | 19295 | 0.0263 | 48 | 461 | 6 | 9 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 509 | 0.0257 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00163 | 0.9945 |
| Neratinib | 180622_MC_14 | 19417 | 0.0267 | 53 | 467 | 7 | 21 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_2 | 520 | 0.0261 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00201 | 0.9977 |
| Neratinib | 180622_MC_14 | 19230 | 0.0215 | 46 | 369 | 14 | 20 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_3 | 415 | 0.0211 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00294 | 0.9928 |
| Neratinib | 180622_MC_15 | 19933 | 0.0268 | 67 | 469 | 3 | 9 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_4 | 536 | 0.0262 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00212 | 1.0110 |
| Neratinib | 180622_MC_15 | 19250 | 0.0247 | 77 | 401 | 8 | 7 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_5 | 478 | 0.0242 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00016 | 0.9934 |
| Neratinib | 180622_MC_15 | 20038 | 0.0206 | 69 | 345 | 14 | 14 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_6 | 414 | 0.0202 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00383 | 1.0137 |
| Neratinib | 180622_MC_16 | 19670 | 0.0301 | 100 | 495 | 5 | 5 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 595 | 0.0294 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00529 | 1.0043 |
| Neratinib | 180622_MC_16 | 19570 | 0.0276 | 121 | 422 | 9 | 12 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 543 | 0.0270 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00293 | 1.0017 |
| Neratinib | 180622_MC_16 | 19318 | 0.0219 | 68 | 356 | 14 | 22 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 424 | 0.0215 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00259 | 0.9951 |
| Neratinib | 180622_MC_14 | 17314 | 0.0203 | 38 | 314 | 5 | 8 | Neratinib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_1 | 352 | 0.0199 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00414 | 0.9407 |
| Neratinib | 180622_MC_14 | 16879 | 0.0204 | 42 | 304 | 6 | 12 | Neratinib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_2 | 346 | 0.0201 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00398 | 0.9283 |
| Neratinib | 180622_MC_14 | 16926 | 0.0231 | 54 | 338 | 7 | 18 | Neratinib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_3 | 392 | 0.0226 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00143 | 0.9297 |
| Neratinib | 180622_MC_15 | 18745 | 0.0205 | 57 | 329 | 4 | 5 | Neratinib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_4 | 386 | 0.0202 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00389 | 0.9800 |
| Neratinib | 180622_MC_15 | 18829 | 0.0219 | 57 | 357 | 5 | 10 | Neratinib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_5 | 414 | 0.0215 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00255 | 0.9823 |