LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Etoposide | 180622_MC_14 | 11802 | 0.0187 | 54 | 168 | 14 | 17 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_3 | 222 | 0.0185 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00560 | 0.7618 |
Etoposide | 180622_MC_15 | 11958 | 0.0191 | 87 | 143 | 7 | 14 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_4 | 230 | 0.0189 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00520 | 0.7676 |
Etoposide | 180622_MC_15 | 12121 | 0.0160 | 58 | 137 | 11 | 16 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_5 | 195 | 0.0158 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00823 | 0.7737 |
Etoposide | 180622_MC_15 | 12160 | 0.0181 | 70 | 151 | 11 | 20 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_6 | 221 | 0.0178 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00622 | 0.7751 |
Etoposide | 180622_MC_16 | 12559 | 0.0210 | 126 | 140 | 3 | 22 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_7 | 266 | 0.0207 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00333 | 0.7896 |
Etoposide | 180622_MC_16 | 13724 | 0.0245 | 124 | 215 | 11 | 13 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_8 | 339 | 0.0241 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00004 | 0.8302 |
Etoposide | 180622_MC_16 | 13531 | 0.0225 | 118 | 189 | 11 | 17 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_9 | 307 | 0.0222 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00188 | 0.8236 |
Etoposide | 180622_MC_14 | 5131 | 0.0386 | 96 | 106 | 8 | 4 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_1 | 202 | 0.0379 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01381 | 0.4277 |
Etoposide | 180622_MC_14 | 5376 | 0.0336 | 97 | 87 | 10 | 6 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_2 | 184 | 0.0331 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00903 | 0.4446 |
Etoposide | 180622_MC_14 | 5292 | 0.0245 | 53 | 78 | 11 | 8 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_3 | 131 | 0.0242 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00009 | 0.4389 |
Etoposide | 180622_MC_15 | 5691 | 0.0409 | 135 | 103 | 8 | 3 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_4 | 238 | 0.0401 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01607 | 0.4655 |
Etoposide | 180622_MC_15 | 5867 | 0.0374 | 119 | 105 | 9 | 7 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_5 | 224 | 0.0368 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01271 | 0.4768 |
Etoposide | 180622_MC_15 | 5827 | 0.0289 | 93 | 78 | 11 | 7 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_6 | 171 | 0.0285 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00444 | 0.4743 |
Etoposide | 180622_MC_16 | 7329 | 0.0263 | 91 | 104 | 6 | 22 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_7 | 195 | 0.0259 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00185 | 0.5621 |
Etoposide | 180622_MC_16 | 7094 | 0.0215 | 78 | 76 | 8 | 16 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_8 | 154 | 0.0212 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00282 | 0.5493 |
Etoposide | 180622_MC_16 | 7604 | 0.0243 | 90 | 97 | 10 | 11 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_9 | 187 | 0.0240 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00007 | 0.5767 |
Etoposide | 180622_MC_14 | 1415 | 0.0817 | 78 | 44 | 3 | 6 | Etoposide | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_1 | 122 | 0.0794 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05531 | 0.0314 |
Etoposide | 180622_MC_14 | 1717 | 0.0787 | 99 | 44 | 6 | 17 | Etoposide | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_2 | 143 | 0.0769 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05281 | 0.0830 |
Etoposide | 180622_MC_14 | 1665 | 0.0646 | 69 | 43 | 6 | 18 | Etoposide | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_3 | 112 | 0.0630 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03896 | 0.0746 |
Etoposide | 180622_MC_15 | 1835 | 0.0728 | 103 | 38 | 3 | 8 | Etoposide | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_4 | 141 | 0.0714 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04729 | 0.1013 |
Etoposide | 180622_MC_15 | 1867 | 0.0752 | 102 | 46 | 7 | 16 | Etoposide | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_5 | 148 | 0.0734 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04938 | 0.1061 |
Etoposide | 180622_MC_15 | 1757 | 0.0951 | 136 | 44 | 8 | 5 | Etoposide | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_6 | 180 | 0.0929 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.06886 | 0.0893 |
Etoposide | 180622_MC_16 | 2109 | 0.1365 | 162 | 148 | 3 | 3 | Etoposide | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_7 | 310 | 0.1282 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.10408 | 0.1407 |
Etoposide | 180622_MC_16 | 2222 | 0.0613 | 94 | 48 | 10 | 12 | Etoposide | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_8 | 142 | 0.0601 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03600 | 0.1558 |
Etoposide | 180622_MC_16 | 2146 | 0.0992 | 163 | 66 | 11 | 9 | Etoposide | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_9 | 229 | 0.0964 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.07235 | 0.1457 |