LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vorinostat | 180622_MC_14 | 20075 | 0.0259 | 44 | 478 | 5 | 13 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 522 | 0.0253 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00128 | 1.0146 |
| Vorinostat | 180622_MC_14 | 19462 | 0.0239 | 42 | 424 | 6 | 11 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 466 | 0.0234 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00068 | 0.9989 |
| Vorinostat | 180622_MC_14 | 19292 | 0.0234 | 64 | 388 | 8 | 10 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_3 | 452 | 0.0229 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00117 | 0.9945 |
| Vorinostat | 180622_MC_15 | 19010 | 0.0200 | 84 | 298 | 7 | 7 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_4 | 382 | 0.0197 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00437 | 0.9871 |
| Vorinostat | 180622_MC_15 | 19105 | 0.0215 | 64 | 348 | 8 | 22 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_5 | 412 | 0.0211 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00296 | 0.9896 |
| Vorinostat | 180622_MC_15 | 19544 | 0.0261 | 87 | 426 | 9 | 3 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_6 | 513 | 0.0256 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00151 | 1.0010 |
| Vorinostat | 180622_MC_16 | 19753 | 0.0247 | 93 | 397 | 5 | 21 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_7 | 490 | 0.0242 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00014 | 1.0064 |
| Vorinostat | 180622_MC_16 | 19975 | 0.0235 | 72 | 400 | 8 | 12 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 472 | 0.0231 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00098 | 1.0121 |
| Vorinostat | 180622_MC_16 | 19913 | 0.0248 | 78 | 417 | 12 | 18 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 495 | 0.0243 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00019 | 1.0105 |
| Vorinostat | 180622_MC_14 | 19322 | 0.0289 | 72 | 489 | 8 | 12 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 561 | 0.0282 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00415 | 0.9952 |
| Vorinostat | 180622_MC_14 | 19492 | 0.0202 | 27 | 368 | 13 | 17 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_2 | 395 | 0.0199 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00421 | 0.9997 |
| Vorinostat | 180622_MC_14 | 19196 | 0.0272 | 37 | 487 | 13 | 19 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_3 | 524 | 0.0266 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00250 | 0.9920 |
| Vorinostat | 180622_MC_15 | 19159 | 0.0245 | 64 | 407 | 7 | 6 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_4 | 471 | 0.0240 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00007 | 0.9910 |
| Vorinostat | 180622_MC_15 | 19742 | 0.0208 | 52 | 359 | 7 | 12 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_5 | 411 | 0.0204 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00367 | 1.0061 |
| Vorinostat | 180622_MC_15 | 18881 | 0.0200 | 52 | 326 | 11 | 12 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_6 | 378 | 0.0196 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00444 | 0.9836 |
| Vorinostat | 180622_MC_16 | 20441 | 0.0287 | 92 | 497 | 3 | 18 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 589 | 0.0280 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00394 | 1.0238 |
| Vorinostat | 180622_MC_16 | 19265 | 0.0232 | 85 | 364 | 5 | 22 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 449 | 0.0228 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00129 | 0.9938 |
| Vorinostat | 180622_MC_16 | 19676 | 0.0292 | 79 | 497 | 10 | 19 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 576 | 0.0284 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00437 | 1.0044 |
| Vorinostat | 180622_MC_14 | 19206 | 0.0260 | 44 | 457 | 6 | 19 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_1 | 501 | 0.0254 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00135 | 0.9922 |
| Vorinostat | 180622_MC_14 | 19402 | 0.0274 | 47 | 486 | 8 | 18 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_2 | 533 | 0.0267 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00267 | 0.9973 |
| Vorinostat | 180622_MC_14 | 19004 | 0.0204 | 30 | 358 | 14 | 6 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_3 | 388 | 0.0200 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00406 | 0.9869 |
| Vorinostat | 180622_MC_15 | 18828 | 0.0220 | 67 | 349 | 4 | 4 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_4 | 416 | 0.0216 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00245 | 0.9822 |
| Vorinostat | 180622_MC_15 | 18704 | 0.0208 | 49 | 341 | 7 | 8 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_5 | 390 | 0.0204 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00364 | 0.9789 |
| Vorinostat | 180622_MC_15 | 19525 | 0.0256 | 59 | 443 | 9 | 21 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_6 | 502 | 0.0251 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00100 | 1.0005 |
| Vorinostat | 180622_MC_16 | 18627 | 0.0257 | 123 | 359 | 5 | 12 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_7 | 482 | 0.0252 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00116 | 0.9769 |