LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Taxol | 180615_MC_07 | 12551 | 0.0196 | 56 | 191 | 10 | 5 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_4 | 247 | 0.0193 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00410 | 1.0044 |
| Taxol | 180615_MC_07 | 10922 | 0.0260 | 66 | 220 | 12 | 4 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_5 | 286 | 0.0255 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00212 | 0.9422 |
| Taxol | 180615_MC_07 | 11388 | 0.0220 | 25 | 226 | 13 | 12 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_6 | 251 | 0.0216 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00183 | 0.9607 |
| Taxol | 180615_MC_08 | 11734 | 0.0331 | 92 | 300 | 10 | 15 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_7 | 392 | 0.0323 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00893 | 0.9741 |
| Taxol | 180615_MC_08 | 11789 | 0.0227 | 48 | 221 | 10 | 18 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_8 | 269 | 0.0223 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00109 | 0.9762 |
| Taxol | 180615_MC_08 | 10845 | 0.0300 | 48 | 279 | 12 | 12 | Paclitaxel | 0.000998 | treatment | 72 | 1 | MCF10A-GM_9 | 327 | 0.0293 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00587 | 0.9391 |
| Taxol | 180615_MC_06 | 5252 | 0.0874 | 79 | 387 | 5 | 21 | Paclitaxel | 0.002994 | treatment | 72 | 1 | MCF10A-GM_1 | 466 | 0.0815 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.05810 | 0.6448 |
| Taxol | 180615_MC_06 | 4001 | 0.1177 | 95 | 387 | 7 | 16 | Paclitaxel | 0.002994 | treatment | 72 | 1 | MCF10A-GM_2 | 482 | 0.1075 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08412 | 0.5463 |
| Taxol | 180615_MC_06 | 3877 | 0.0968 | 60 | 321 | 7 | 22 | Paclitaxel | 0.002994 | treatment | 72 | 1 | MCF10A-GM_3 | 381 | 0.0895 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.06608 | 0.5353 |
| Taxol | 180615_MC_07 | 4560 | 0.0866 | 60 | 340 | 9 | 9 | Paclitaxel | 0.002994 | treatment | 72 | 1 | MCF10A-GM_4 | 400 | 0.0806 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.05725 | 0.5929 |
| Taxol | 180615_MC_07 | 4813 | 0.0933 | 95 | 363 | 12 | 12 | Paclitaxel | 0.002994 | treatment | 72 | 1 | MCF10A-GM_5 | 458 | 0.0869 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.06349 | 0.6126 |
| Taxol | 180615_MC_07 | 4237 | 0.0900 | 97 | 293 | 14 | 6 | Paclitaxel | 0.002994 | treatment | 72 | 1 | MCF10A-GM_6 | 390 | 0.0843 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.06089 | 0.5666 |
| Taxol | 180615_MC_08 | 5221 | 0.0751 | 77 | 321 | 5 | 15 | Paclitaxel | 0.002994 | treatment | 72 | 1 | MCF10A-GM_7 | 398 | 0.0708 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04743 | 0.6426 |
| Taxol | 180615_MC_08 | 5993 | 0.0760 | 100 | 363 | 8 | 8 | Paclitaxel | 0.002994 | treatment | 72 | 1 | MCF10A-GM_8 | 463 | 0.0717 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04832 | 0.6948 |
| Taxol | 180615_MC_08 | 4892 | 0.0771 | 52 | 329 | 13 | 11 | Paclitaxel | 0.002994 | treatment | 72 | 1 | MCF10A-GM_9 | 381 | 0.0723 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04886 | 0.6185 |
| Taxol | 180615_MC_06 | 913 | 0.3114 | 60 | 243 | 3 | 9 | Paclitaxel | 0.00998 | treatment | 72 | 1 | MCF10A-GM_1 | 303 | 0.2492 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.22578 | 0.1058 |
| Taxol | 180615_MC_06 | 1028 | 0.4569 | 191 | 366 | 4 | 16 | Paclitaxel | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 557 | 0.3514 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.32802 | 0.1359 |
| Taxol | 180615_MC_06 | 829 | 0.5359 | 244 | 331 | 4 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 575 | 0.4095 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.38615 | 0.0818 |
| Taxol | 180615_MC_07 | 1030 | 0.3517 | 79 | 311 | 5 | 16 | Paclitaxel | 0.00998 | treatment | 72 | 1 | MCF10A-GM_4 | 390 | 0.2746 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.25125 | 0.1364 |
| Taxol | 180615_MC_07 | 881 | 0.3828 | 62 | 299 | 11 | 11 | Paclitaxel | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 361 | 0.2907 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.26726 | 0.0968 |
| Taxol | 180615_MC_07 | 1066 | 0.3873 | 83 | 362 | 13 | 5 | Paclitaxel | 0.00998 | treatment | 72 | 1 | MCF10A-GM_6 | 445 | 0.2945 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.27111 | 0.1453 |
| Taxol | 180615_MC_08 | 881 | 0.4025 | 140 | 271 | 3 | 14 | Paclitaxel | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 411 | 0.3181 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.29471 | 0.0968 |
| Taxol | 180615_MC_08 | 794 | 0.4711 | 123 | 309 | 12 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 1 | MCF10A-GM_7 | 432 | 0.3524 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.32897 | 0.0713 |
| Taxol | 180615_MC_08 | 1037 | 0.4015 | 141 | 332 | 14 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 1 | MCF10A-GM_8 | 473 | 0.3132 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.28985 | 0.1382 |
| Taxol | 180615_MC_06 | 272 | 0.9679 | 196 | 257 | 3 | 19 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_1 | 453 | 0.6248 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.60143 | -0.1600 |