LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpelisib | 180615_MC_07 | 7478 | 0.0193 | 30 | 115 | 11 | 6 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_6 | 145 | 0.0190 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00438 | 0.7822 |
| Alpelisib | 180615_MC_08 | 7225 | 0.0319 | 108 | 126 | 4 | 12 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_7 | 234 | 0.0314 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00797 | 0.7683 |
| Alpelisib | 180615_MC_08 | 8266 | 0.0282 | 45 | 189 | 5 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_8 | 234 | 0.0275 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00413 | 0.8232 |
| Alpelisib | 180615_MC_08 | 8566 | 0.0278 | 55 | 185 | 7 | 18 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_9 | 240 | 0.0273 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00386 | 0.8380 |
| Alpelisib | 180615_MC_06 | 5504 | 0.0224 | 24 | 100 | 6 | 13 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_1 | 124 | 0.0220 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00137 | 0.6624 |
| Alpelisib | 180615_MC_06 | 4618 | 0.0181 | 13 | 71 | 8 | 7 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_2 | 84 | 0.0179 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00553 | 0.5975 |
| Alpelisib | 180615_MC_06 | 5807 | 0.0210 | 15 | 107 | 10 | 5 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_3 | 122 | 0.0206 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00282 | 0.6828 |
| Alpelisib | 180615_MC_07 | 5810 | 0.0280 | 83 | 82 | 8 | 4 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_4 | 165 | 0.0276 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00422 | 0.6830 |
| Alpelisib | 180615_MC_07 | 5848 | 0.0252 | 64 | 85 | 10 | 13 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_5 | 149 | 0.0248 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00145 | 0.6855 |
| Alpelisib | 180615_MC_07 | 5978 | 0.0180 | 23 | 85 | 11 | 21 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_6 | 108 | 0.0177 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00565 | 0.6939 |
| Alpelisib | 180615_MC_08 | 5650 | 0.0244 | 44 | 95 | 5 | 19 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_7 | 139 | 0.0240 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00061 | 0.6723 |
| Alpelisib | 180615_MC_08 | 6336 | 0.0302 | 50 | 143 | 10 | 10 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_8 | 193 | 0.0296 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00616 | 0.7164 |
| Alpelisib | 180615_MC_08 | 6106 | 0.0256 | 56 | 102 | 14 | 21 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_9 | 158 | 0.0252 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00183 | 0.7020 |
| Alpelisib | 180615_MC_06 | 2638 | 0.0297 | 22 | 57 | 8 | 17 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_1 | 79 | 0.0291 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00568 | 0.4069 |
| Alpelisib | 180615_MC_06 | 2795 | 0.0379 | 26 | 81 | 9 | 4 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_2 | 107 | 0.0369 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.01347 | 0.4254 |
| Alpelisib | 180615_MC_06 | 2611 | 0.0255 | 19 | 48 | 12 | 19 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_3 | 67 | 0.0250 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00162 | 0.4036 |
| Alpelisib | 180615_MC_07 | 2881 | 0.0335 | 47 | 51 | 3 | 11 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_4 | 98 | 0.0329 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00950 | 0.4353 |
| Alpelisib | 180615_MC_07 | 2850 | 0.0289 | 26 | 57 | 5 | 22 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_5 | 83 | 0.0283 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00490 | 0.4318 |
| Alpelisib | 180615_MC_07 | 2640 | 0.0497 | 74 | 61 | 6 | 16 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_6 | 135 | 0.0486 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.02525 | 0.4071 |
| Alpelisib | 180615_MC_08 | 3423 | 0.0354 | 54 | 69 | 9 | 22 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_7 | 123 | 0.0347 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.01129 | 0.4925 |
| Alpelisib | 180615_MC_08 | 2993 | 0.0442 | 64 | 71 | 10 | 14 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_8 | 135 | 0.0432 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.01976 | 0.4477 |
| Alpelisib | 180615_MC_08 | 3221 | 0.0357 | 53 | 64 | 14 | 14 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_9 | 117 | 0.0351 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.01165 | 0.4721 |
| Dasatinib | 180615_MC_06 | 9996 | 0.0205 | 30 | 176 | 3 | 3 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 206 | 0.0202 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00321 | 0.9035 |
| Dasatinib | 180615_MC_06 | 10451 | 0.0195 | 20 | 184 | 10 | 17 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 204 | 0.0191 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00425 | 0.9229 |
| Dasatinib | 180615_MC_06 | 11347 | 0.0254 | 54 | 236 | 12 | 4 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_3 | 290 | 0.0249 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00152 | 0.9591 |