LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpelisib | 180615_MC_08 | 11950 | 0.0262 | 74 | 241 | 7 | 14 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_8 | 315 | 0.0257 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00228 | 0.9822 |
Alpelisib | 180615_MC_08 | 11686 | 0.0219 | 34 | 223 | 9 | 15 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_9 | 257 | 0.0215 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00188 | 0.9722 |
Alpelisib | 180615_MC_06 | 10148 | 0.0269 | 29 | 245 | 3 | 7 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_1 | 274 | 0.0263 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00289 | 0.9101 |
Alpelisib | 180615_MC_06 | 10623 | 0.0251 | 24 | 243 | 9 | 3 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_2 | 267 | 0.0245 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00112 | 0.9300 |
Alpelisib | 180615_MC_06 | 11187 | 0.0288 | 47 | 277 | 10 | 18 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_3 | 324 | 0.0281 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00475 | 0.9528 |
Alpelisib | 180615_MC_07 | 11396 | 0.0230 | 47 | 216 | 8 | 8 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_4 | 263 | 0.0226 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00084 | 0.9610 |
Alpelisib | 180615_MC_07 | 11277 | 0.0156 | 36 | 141 | 9 | 4 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_5 | 177 | 0.0155 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00795 | 0.9563 |
Alpelisib | 180615_MC_07 | 11820 | 0.0179 | 45 | 167 | 12 | 21 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_6 | 212 | 0.0176 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00578 | 0.9773 |
Alpelisib | 180615_MC_08 | 11047 | 0.0295 | 76 | 252 | 3 | 15 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_7 | 328 | 0.0288 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00544 | 0.9472 |
Alpelisib | 180615_MC_08 | 11750 | 0.0155 | 10 | 172 | 5 | 3 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_8 | 182 | 0.0153 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00815 | 0.9747 |
Alpelisib | 180615_MC_08 | 11288 | 0.0260 | 70 | 225 | 6 | 5 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_9 | 295 | 0.0255 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00207 | 0.9568 |
Alpelisib | 180615_MC_06 | 9315 | 0.0225 | 32 | 178 | 5 | 20 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_1 | 210 | 0.0220 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00135 | 0.8733 |
Alpelisib | 180615_MC_06 | 9406 | 0.0214 | 21 | 181 | 11 | 22 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_2 | 202 | 0.0210 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00237 | 0.8774 |
Alpelisib | 180615_MC_06 | 9634 | 0.0226 | 61 | 158 | 12 | 6 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_3 | 219 | 0.0222 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00117 | 0.8877 |
Alpelisib | 180615_MC_07 | 9393 | 0.0162 | 40 | 113 | 3 | 3 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_4 | 153 | 0.0160 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00737 | 0.8768 |
Alpelisib | 180615_MC_07 | 9770 | 0.0106 | 38 | 66 | 3 | 4 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_5 | 104 | 0.0105 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.01287 | 0.8937 |
Alpelisib | 180615_MC_07 | 10259 | 0.0191 | 50 | 147 | 6 | 17 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_6 | 197 | 0.0188 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00456 | 0.9148 |
Alpelisib | 180615_MC_08 | 8965 | 0.0287 | 80 | 180 | 4 | 14 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_7 | 260 | 0.0282 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00479 | 0.8571 |
Alpelisib | 180615_MC_08 | 10388 | 0.0281 | 81 | 213 | 6 | 12 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_8 | 294 | 0.0275 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00412 | 0.9202 |
Alpelisib | 180615_MC_08 | 10680 | 0.0229 | 42 | 203 | 12 | 22 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_9 | 245 | 0.0224 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00097 | 0.9323 |
Alpelisib | 180615_MC_06 | 7300 | 0.0248 | 24 | 158 | 5 | 3 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_1 | 182 | 0.0243 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00093 | 0.7725 |
Alpelisib | 180615_MC_06 | 8555 | 0.0191 | 23 | 141 | 6 | 5 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_2 | 164 | 0.0188 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00459 | 0.8374 |
Alpelisib | 180615_MC_06 | 8446 | 0.0193 | 19 | 144 | 12 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_3 | 163 | 0.0189 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00446 | 0.8321 |
Alpelisib | 180615_MC_07 | 8397 | 0.0202 | 80 | 91 | 4 | 9 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_4 | 171 | 0.0200 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00344 | 0.8297 |
Alpelisib | 180615_MC_07 | 7625 | 0.0178 | 33 | 103 | 5 | 13 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_5 | 136 | 0.0175 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00587 | 0.7901 |