LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Taxol | 180615_MC_06 | 258 | 0.8747 | 109 | 212 | 11 | 7 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_2 | 321 | 0.5544 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.53101 | -0.1700 |
| Taxol | 180615_MC_06 | 277 | 0.9360 | 223 | 245 | 12 | 16 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_3 | 468 | 0.6282 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.60479 | -0.1565 |
| Taxol | 180615_MC_07 | 254 | 1.0091 | 297 | 259 | 4 | 16 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_4 | 556 | 0.6864 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.66302 | -0.1729 |
| Taxol | 180615_MC_07 | 313 | 0.7609 | 101 | 214 | 9 | 10 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_5 | 315 | 0.5016 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.47819 | -0.1328 |
| Taxol | 180615_MC_07 | 243 | 1.0547 | 232 | 269 | 10 | 14 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_6 | 501 | 0.6734 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.64999 | -0.1812 |
| Taxol | 180615_MC_08 | 202 | 1.0653 | 334 | 237 | 4 | 20 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_7 | 571 | 0.7387 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.71528 | -0.2148 |
| Taxol | 180615_MC_08 | 307 | 0.8643 | 113 | 250 | 7 | 8 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_8 | 363 | 0.5418 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.51839 | -0.1366 |
| Taxol | 180615_MC_08 | 283 | 0.8907 | 156 | 235 | 11 | 18 | Paclitaxel | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_9 | 391 | 0.5801 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.55672 | -0.1524 |
| Taxol | 180615_MC_06 | 232 | 1.1328 | 280 | 300 | 4 | 14 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_1 | 580 | 0.7143 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.69089 | -0.1897 |
| Taxol | 180615_MC_06 | 225 | 1.1189 | 204 | 276 | 5 | 14 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_2 | 480 | 0.6809 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.65745 | -0.1954 |
| Taxol | 180615_MC_06 | 269 | 0.8182 | 61 | 209 | 6 | 7 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_3 | 270 | 0.5009 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.47753 | -0.1621 |
| Taxol | 180615_MC_07 | 161 | 1.1466 | 221 | 217 | 10 | 22 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_4 | 438 | 0.7312 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.70782 | -0.2542 |
| Taxol | 180615_MC_07 | 233 | 0.8143 | 74 | 176 | 11 | 17 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_5 | 250 | 0.5176 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.49420 | -0.1889 |
| Taxol | 180615_MC_07 | 207 | 1.0599 | 177 | 230 | 14 | 20 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_6 | 407 | 0.6629 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.63947 | -0.2104 |
| Taxol | 180615_MC_08 | 168 | 1.0650 | 324 | 200 | 3 | 20 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_7 | 524 | 0.7572 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.73383 | -0.2470 |
| Taxol | 180615_MC_08 | 232 | 0.9828 | 116 | 226 | 9 | 13 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_1 | 342 | 0.5958 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.57242 | -0.1897 |
| Taxol | 180615_MC_08 | 242 | 1.0745 | 174 | 273 | 14 | 5 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_8 | 447 | 0.6488 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.62537 | -0.1819 |
| Taxol | 180615_MC_06 | 187 | 1.1542 | 280 | 259 | 4 | 18 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_1 | 539 | 0.7424 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.71903 | -0.2284 |
| Taxol | 180615_MC_06 | 255 | 0.9435 | 99 | 235 | 7 | 19 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_2 | 334 | 0.5671 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.54366 | -0.1722 |
| Taxol | 180615_MC_06 | 244 | 0.9441 | 60 | 227 | 8 | 3 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_3 | 287 | 0.5405 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.51709 | -0.1804 |
| Taxol | 180615_MC_07 | 179 | 1.1929 | 246 | 261 | 4 | 12 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_4 | 507 | 0.7391 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.71567 | -0.2361 |
| Taxol | 180615_MC_07 | 211 | 1.0503 | 87 | 226 | 11 | 15 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_5 | 313 | 0.5973 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.57393 | -0.2070 |
| Taxol | 180615_MC_07 | 268 | 1.0028 | 94 | 269 | 13 | 9 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_6 | 363 | 0.5753 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.55188 | -0.1628 |
| Taxol | 180615_MC_08 | 179 | 0.9698 | 86 | 171 | 7 | 21 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_4 | 257 | 0.5894 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.56605 | -0.2361 |
| Taxol | 180615_MC_08 | 168 | 1.2302 | 262 | 267 | 10 | 22 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_7 | 529 | 0.7590 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.73557 | -0.2470 |