Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)

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Cell Small Molecule Treatment Duration GR50 GRmax GR_AOC GEC50 GRinf hGR
HCC1419 Vialinin A 72
6.52356293031
 -0.5490 0.2630 13.1152 -0.7812 1.3473
HCC202 z-VAE(OMe)-fmk 72
inf
 1.0085 0.0421 0.0000 0.9739 0.0100
PDXHCI002 z-VAE(OMe)-fmk 72
inf
 0.9278 0.0585 0.0000 0.9445 0.0100
HCC1419 z-VAE(OMe)-fmk 72
inf
 0.9275 0.0463 0.0000 0.9622 0.0100
CAMA-1 z-VAE(OMe)-fmk 72
inf
 0.9619 0.0262 0.0000 0.9726 0.0100
BT-549 z-VAE(OMe)-fmk 72
inf
 0.9727 0.0182 0.0000 0.9828 0.0100
HCC1937 z-VAE(OMe)-fmk 72
inf
 0.9933 -0.0106 0.0000 1.0000 0.0100
MCF 10A z-VAE(OMe)-fmk 72
inf
 0.9979 0.0012 0.0000 0.9999 0.0100
HCC1428 z-VAE(OMe)-fmk 72
inf
 0.9944 0.0566 0.0000 0.9577 0.0100
PDX1328 z-VAE(OMe)-fmk 72
inf
 1.0551 0.0297 0.0000 0.9884 0.0100
SK-BR-3 z-VAE(OMe)-fmk 72
inf
 0.9573 0.0430 0.0000 0.9575 0.0100
T47D z-VAE(OMe)-fmk 72
inf
 0.9468 0.0261 0.0000 0.9749 0.0100
MDA-MB-231 z-VAE(OMe)-fmk 72
inf
 0.9382 0.0024 0.0000 0.9922 0.0100
HCC1954 z-VAE(OMe)-fmk 72
inf
 1.0513 0.0385 0.0000 0.9751 0.0100
MDA-MB-361 z-VAE(OMe)-fmk 72
inf
 0.9096 0.0284 0.0000 0.9738 0.0100
Hs 578T z-VAE(OMe)-fmk 72
inf
 0.9948 0.0176 0.0000 0.9832 0.0100
HCC1500 z-VAE(OMe)-fmk 72
inf
 1.1021 0.0136 0.0000 1.0000 0.0100
MCF7 z-VAE(OMe)-fmk 72
inf
 1.0118 -0.0177 0.0000 1.0000 0.0100
HCC1806 z-VAE(OMe)-fmk 72
inf
 0.9581 0.0231 0.0000 0.9783 0.0100
PDX1258 z-VAE(OMe)-fmk 72
inf
 0.9262 0.0692 0.0000 0.9516 0.0100
MDA-MB-134-VI z-VAE(OMe)-fmk 72
inf
 0.9937 0.1205 0.0000 0.8924 0.0100
BT-20 z-VAE(OMe)-fmk 72
inf
 0.9762 0.0198 0.0000 0.9890 0.0100