Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)
Small Molecules Studied
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| HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
|---|---|---|---|---|---|
| 10265-2 | Pevonedistat | MLN 4924; MLN-4924; MLN4924 | LSM-6263 |  | 16720766 |
| 10479-2 | Mitoxantrone | CL 232325; CL-232325; DHAQ; Novantron; Novantrone | LSM-2481 |  | 4212 |
| 10543-1 | b-AP15 |  | 5351435 | ||
| 10544-2 | STK547622 | GTPL8661; LDN-91946 |  | 950368 | |
| 10545-1 | LDN57444 | LDN-57444; Ubiquitin Thiolesterase L1 Inhibitor; UCH-L1 Inhibitor |  | 24906255 | |
| 10546-1 | P22077 | P 22077 |  | 46931953 | |
| 10547-1 | Trifluoperazine | Eskazine; Flurazine; Jatroneural; Modalina; Stelazine; Terfluzine; Trifluoperazina; Trifluoroperazine; Trifluperazine; Triflurin; Triftazin; Triperazine |  | 5566 | |
| 10548-1 | 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one | STK854993 |  | 2913480 | |
| 10549-1 | Pimozide | McN-JR-6238; Neoperidole; Opiran; Orap; Pimozidum |  | 16362 | |
| 10550-1 | GW7647 | GW 7647; GW-7647; GW647 |  | 3392731 | |
| 10551-1 | MI-2 | MI 2; MALT1 inhibitor |  | 45942672 | |
| 10552-1 | Sepantronium | YM155 |  | 10126189 | |
| 10554-1 | HBX 41108 |  | 16065773 | ||
| 10556-1 | Doxycycline | Doxytetracycline; Monodox; Oracea; Vibramycin |  | 54671203 | |
| 10558-1 | Degrasyn | WP 1130; WP1130; WP-1130 |  | 11222830 | |
| 10559-1 | SJB3-019A |  | 78358325 | ||
| 10560-1 | IU1 | IU-1 |  | 675434 | |
| 10561-1 | Spautin-1 | Spautin 1 |  | 51037431 | |
| 10562-1 | Vialinin A | Terrestrin A |  | 11563133 | |
| 11942-1 | HY-17541A | Cysteine Protease inhibitor hydrochloride |  | ||
| 11943-1 | SJB2-043 | 2-Phenylbenzo[f][1,3]benzoxazole-4,9-dione |  | 509070 | |
| 11945-1 | 1247825-37-1 | 4-cyano-5-(3,5-dichloropyridin-4-yl)sulfanyl-N-(4-methylsulfonylphenyl)thiophene-2-carboxamide; USP7/USP47 inhibitor |  | 51031028 | |
| 11946-1 | HY-50737A | DUBs-IN-2 |  | 16065491 | |
| 11947-1 | HY-50736 | DUBs-IN-1 |  | 16065490 | |
| 11948-1 | ML-323 | ML323; ML 323 |  | 60167849 |