Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)
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| Cell | Small Molecule | Treatment Duration | GR50 | GRmax | GR_AOC | GEC50 | GRinf | hGR |
|---|---|---|---|---|---|---|---|---|
| HCC1937 | Sepantronium | 72 | 0.0274217558915 | -0.5570 | 1.2238 | 0.0525 | -0.5494 | 1.1409 |
| PDX1258 | Sepantronium | 72 | 0.0944990954 | -0.5758 | 0.9903 | 0.1955 | -0.5482 | 1.0184 |
| HCC1806 | Sepantronium | 72 | 0.0194330717839 | -0.2281 | 1.0647 | 0.0221 | -0.1914 | 2.4836 |
| SK-BR-3 | Sepantronium | 72 | 0.0223899931737 | -0.6896 | 1.3675 | 0.0376 | -0.6471 | 1.6002 |
| PDX1328 | SJB2-043 | 72 | 0.283039978056 | -0.9550 | 0.9369 | 0.3776 | -0.9607 | 3.7191 |
| MDA-MB-361 | SJB2-043 | 72 | 1.59047305005 | -0.2559 | 0.3538 | 1.7814 | -0.2365 | 3.4159 |
| HCC1419 | SJB2-043 | 72 | 0.513272955065 | -0.6875 | 0.6450 | 0.9630 | -0.7220 | 1.4201 |
| MCF 10A | SJB2-043 | 72 | 0.862612545381 | -0.1149 | 0.4174 | 0.9321 | -0.1040 | 2.4388 |
| MDA-MB-134-VI | SJB2-043 | 72 | 1.00401948456 | -0.3627 | 0.4871 | 1.7779 | -0.4717 | 1.1627 |
| PDX1258 | SJB2-043 | 72 | 0.885786050221 | -0.4791 | 0.4693 | 1.0043 | -0.4368 | 5.0000 |
| Hs 578T | SJB2-043 | 72 | 0.328943396017 | -0.5256 | 0.7088 | 0.4990 | -0.5345 | 1.7452 |
| HCC1806 | SJB2-043 | 72 | 4.05064367394 | -0.1302 | 0.2617 | 4.3188 | -0.1361 | 3.7560 |
| HCC1428 | SJB2-043 | 72 | 0.829968735356 | -0.6237 | 0.5416 | 1.3763 | -0.6396 | 1.6289 |
| MCF7 | SJB2-043 | 72 | 0.361790238142 | -0.2773 | 0.6009 | 0.4120 | -0.2857 | 3.4782 |
| HCC1500 | SJB2-043 | 72 | 0.201434109876 | -0.4925 | 0.7459 | 0.2844 | -0.4547 | 1.8761 |
| HCC202 | SJB2-043 | 72 | 0.34979801402 | -0.6438 | 0.6718 | 0.6597 | -0.6491 | 1.3117 |
| BT-549 | SJB2-043 | 72 | 0.795024880409 | -0.3792 | 0.5237 | 0.9638 | -0.3726 | 2.8926 |
| CAMA-1 | SJB2-043 | 72 | 0.372483737956 | -0.4977 | 0.7091 | 0.4732 | -0.5024 | 2.9069 |
| MDA-MB-231 | SJB2-043 | 72 | 0.531717815307 | -0.3147 | 0.5316 | 0.6346 | -0.2713 | 2.4513 |
| SK-BR-3 | SJB2-043 | 72 | 0.397342856958 | -0.6773 | 0.7194 | 0.5909 | -0.6730 | 2.1483 |
| T47D | SJB2-043 | 72 | 0.418884416082 | -0.3821 | 0.5842 | 0.6165 | -0.3642 | 1.4158 |
| HCC1954 | SJB2-043 | 72 | 1.24122713519 | -0.3522 | 0.3712 | 1.3752 | -0.2369 | 3.7831 |
| HCC1937 | SJB2-043 | 72 | 0.396049351375 | -0.5581 | 0.6542 | 0.6443 | -0.5754 | 1.5740 |
| BT-20 | SJB2-043 | 72 | 0.626589137637 | -0.6216 | 0.5257 | 0.7914 | -0.6048 | 3.3941 |
| PDXHCI002 | SJB2-043 | 72 | 0.744329070426 | -0.3405 | 0.5118 | 0.9155 | -0.3386 | 2.4985 |