Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)

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Cell Small Molecule Treatment Duration GR50 GRmax GR_AOC GEC50 GRinf hGR
MDA-MB-231 HY-50737A 72
23.698925903
 0.0363 0.0855 26.1146 -0.1424 2.5817
HCC1954 HY-50737A 72
0.358997904545
 -0.5501 0.8394 0.6036 -0.5719 1.4677
MDA-MB-134-VI IU1 72
inf
 0.5672 0.1770 1.5029 0.5472 5.0000
Hs 578T IU1 72
63.4449771188
 0.6256 0.0170 49.9183 0.2532 2.9451
HCC1937 IU1 72
inf
 0.8662 0.0085 0.0000 0.9831 0.0100
HCC1419 IU1 72
inf
 0.6981 0.0438 17.0535 0.7480 5.0000
MCF7 IU1 72
inf
 0.7464 0.0252 29.2117 0.7291 5.0000
HCC1806 IU1 72
116.251943958
 0.8831 0.0051 197.1530 -0.9493 2.0147
HCC202 IU1 72
inf
 0.7641 -0.0242 0.0000 0.9954 0.0100
PDXHCI002 IU1 72
inf
 0.7347 0.0713 0.0000 0.9096 0.0100
BT-20 IU1 72
inf
 1.1490 -0.1850 0.0000 1.0000 0.0100
HCC1500 IU1 72
inf
 0.6977 0.0082 0.0000 0.9531 0.0100
BT-549 IU1 72
inf
 0.9301 0.0193 16.1731 0.9293 3.6587
MDA-MB-361 IU1 72
inf
 0.7838 -0.0464 0.0000 1.0000 0.0100
MDA-MB-231 IU1 72
inf
 0.8503 0.0614 0.0000 0.9320 0.0100
CAMA-1 IU1 72
inf
 0.7385 0.0833 0.9170 0.8015 5.0000
MCF 10A IU1 72
inf
 0.9050 0.0119 30.9108 0.8598 1.4169
T47D IU1 72
inf
 0.5230 0.0543 0.0000 0.9042 0.0100
SK-BR-3 IU1 72
206.741150231
 0.7547 0.0343 99.4820 0.2546 0.9732
PDX1328 IU1 72
inf
 0.6034 0.0522 0.0000 0.9321 0.0100
PDX1258 IU1 72
inf
 0.7739 0.0478 9.3467 0.8104 5.0000
HCC1954 IU1 72
inf
 0.7969 0.0254 8.5142 0.7979 1.8182
HCC1428 IU1 72
inf
 0.7506 0.0316 0.0000 0.9483 0.0100
MDA-MB-134-VI LDN57444 72
inf
 0.4981 0.0089 0.0000 0.9326 0.0100
Hs 578T LDN57444 72
19.4934085155
 -0.0884 0.1662 33.0205 -0.6495 1.5795