Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)

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Cell Small Molecule Treatment Duration GR50 GRmax GR_AOC GEC50 GRinf hGR
HCC1500 1247825-37-1 72
9.28838157031
 -0.3852 0.2439 10.3909 -0.3761 5.0000
PDX1328 1247825-37-1 72
22.1349466658
 -0.4424 0.1065 25.3891 -0.4927 5.0000
MCF7 P22077 72
10.7385958579
 -0.3409 0.2082 11.8606 -0.3218 5.0000
Hs 578T 1247825-37-1 72
10.9138626563
 -0.3555 0.2306 11.9637 -0.2914 5.0000
CAMA-1 IU1 72
inf
 0.7385 0.0833 0.9170 0.8015 5.0000
MCF7 HY-17542 72
inf
 0.9160 0.0071 30.5166 0.9088 5.0000
PDXHCI002 Trifluoperazine 72
3.81665897006
 -0.5151 0.4939 4.3815 -0.4970 5.0000
HCC202 LDN57444 72
35.5631753073
 0.1261 0.0350 36.2274 -0.0485 5.0000
MDA-MB-134-VI 1247825-37-1 72
10.4154396199
 -0.1095 0.2026 10.7700 -0.0911 5.0000
PDX1258 SJB2-043 72
0.885786050221
 -0.4791 0.4693 1.0043 -0.4368 5.0000
MCF 10A Trifluoperazine 72
13.7054527208
 -0.3753 0.2032 15.3336 -0.3764 5.0000
CAMA-1 1247825-37-1 72
12.5263467336
 -0.2434 0.1646 13.4850 -0.2229 5.0000
PDX1258 PB49673382 72
5.45211284753
 0.1759 0.2476 5.0473 0.1600 5.0000
HCC1954 Doxycycline 72
23.9368215941
 0.0566 0.0431 24.0739 -0.0145 5.0000
HCC1954 Degrasyn 72
3.28733078255
 -0.6866 0.5156 3.9070 -0.6857 5.0000
PDX1258 IU1 72
inf
 0.7739 0.0478 9.3467 0.8104 5.0000
MDA-MB-134-VI IU1 72
inf
 0.5672 0.1770 1.5029 0.5472 5.0000
MDA-MB-231 PB49673382 72
8.96593855475
 -0.0627 0.1864 9.0711 -0.0300 5.0000
HCC1806 HY-50737A 72
11.8311020156
 -0.2747 0.2199 12.8932 -0.2685 5.0000
MDA-MB-134-VI PB49673382 72
12.4536117294
 -0.0102 0.1233 11.0745 0.2220 5.0000
PDX1258 1247825-37-1 72
13.2811411655
 0.1210 0.0958 12.5137 0.1287 5.0000
MDA-MB-361 Trifluoperazine 72
9.45447519759
 -0.7673 0.3443 11.3498 -0.7466 5.0000