Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)

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Cell Small Molecule Treatment Duration GR50 GRmax GR_AOC GEC50 GRinf hGR
SK-BR-3 USP7-IN-1 72
62.2210904101
 0.5764 0.0588 133.0943 -1.0000 1.4449
MCF7 ML-323 72
34.9041902184
 0.3934 0.1213 138.0045 -1.0000 0.7992
CAMA-1 SB1-F-22 72
43.6088606735
 0.4408 0.0565 156.5267 -1.0000 0.8597
BT-549 USP7-IN-1 72
94.531181628
 0.8209 0.0177 166.1357 -1.0000 1.9483
HCC1806 IU1 72
116.251943958
 0.8831 0.0051 197.1530 -0.9493 2.0147
MCF 10A HY-17542 72
122.726417103
 0.9130 0.0108 200.5533 -1.0000 2.2369
CAMA-1 USP7-IN-1 72
90.407874652
 0.7005 0.0265 239.6012 -1.0000 1.1272
SK-BR-3 ML-323 72
71.5457262907
 0.6083 0.0659 250.9976 -1.0000 0.8753
MCF 10A 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one 72
738.9217363
 0.8943 0.0150 255.4365 0.3311 1.0216
T47D SB1-F-22 72
156.804339896
 0.7134 0.0621 286.2396 -0.2481 0.6696
MDA-MB-231 ML-323 72
60.8635339383
 0.5091 0.0928 299.6220 -1.0000 0.6893
T47D USP7-IN-1 72
35.2358506575
 0.3921 0.1491 300.7608 -1.0000 0.5124
PDX1328 Spautin-1 72
43.5833222905
 0.4636 0.1399 310.0635 -1.0000 0.5599
MCF 10A ML-323 72
66.3873318694
 0.5514 0.0860 333.5126 -1.0000 0.6806
HCC1937 ML-323 72
86.9696327252
 0.6194 0.0517 375.1322 -0.9832 0.7439
MCF 10A USP7-IN-1 72
130.869645041
 0.7420 0.0432 404.8308 -0.8498 0.8794
HCC1806 USP7-IN-1 72
154.815652356
 0.8197 0.0286 421.1954 -1.0000 1.0977
BT-549 ML-323 72
74.3999913582
 0.5763 0.0892 442.2433 -1.0000 0.6164
PDX1258 SB1-F-22 72
141.822011334
 0.6791 0.0519 862.0159 -1.0000 0.6088
HCC1954 ML-323 72
85.295133896
 0.5808 0.1325 985.9258 -1.0000 0.4489
BT-20 ML-323 72
211.396631725
 0.7311 0.0653 1563.4058 -1.0000 0.5491
Hs 578T ML-323 72
133.678939825
 0.6153 0.1131 2077.0523 -1.0000 0.4005