Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDX1258 | Degrasyn | 9.992797406 | -0.4530 | 0.48870 |
| PDX1258 | Degrasyn | 31.6 | -0.5732 | 0.55781 |
| PDX1258 | Degrasyn | 50.0 | -0.5884 | 0.38206 |
| PDX1258 | Sepantronium | 0.009992797 | 0.9398 | 0.02237 |
| PDX1258 | Sepantronium | 0.0316 | 0.8717 | 0.04707 |
| PDX1258 | Sepantronium | 0.099927974 | 0.4149 | 0.17915 |
| PDX1258 | Sepantronium | 0.316 | 0.0395 | 0.38160 |
| PDX1258 | Sepantronium | 0.999279741 | -0.2774 | 0.50068 |
| PDX1258 | Sepantronium | 3.16 | -0.4311 | 0.57633 |
| PDX1258 | Sepantronium | 9.992797406 | -0.5187 | 0.59079 |
| PDX1258 | Sepantronium | 31.6 | -0.5472 | 0.59185 |
| PDX1258 | Sepantronium | 50.0 | -0.5758 | 0.40162 |
| PDX1258 | z-VAE(OMe)-fmk | 0.009992797 | 1.0845 | -0.01224 |
| PDX1258 | z-VAE(OMe)-fmk | 0.0316 | 0.9291 | -0.00614 |
| PDX1258 | z-VAE(OMe)-fmk | 0.099927974 | 0.9711 | -0.00842 |
| PDX1258 | z-VAE(OMe)-fmk | 0.316 | 0.8888 | 0.01113 |
| PDX1258 | z-VAE(OMe)-fmk | 0.999279741 | 0.8428 | 0.01269 |
| PDX1258 | z-VAE(OMe)-fmk | 3.16 | 0.9948 | -0.00103 |
| PDX1258 | z-VAE(OMe)-fmk | 9.992797406 | 0.8566 | 0.00486 |
| PDX1258 | z-VAE(OMe)-fmk | 31.6 | 0.9262 | 0.00333 |
| PDX1258 | z-VAE(OMe)-fmk | 50.0 | 1.0703 | 0.01206 |
| PDX1328 | 1247825-37-1 | 0.009992797 | 1.0100 | 0.00094 |
| PDX1328 | 1247825-37-1 | 0.0316 | 1.0443 | 0.00774 |
| PDX1328 | 1247825-37-1 | 0.099927974 | 0.9413 | 0.00306 |
| PDX1328 | 1247825-37-1 | 0.316 | 0.8917 | -0.00679 |