Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDX1258 | b-AP15 | 50.0 | -0.6381 | 0.40088 |
| PDX1258 | USP7-IN-1 | 0.009992797 | 1.0790 | 0.01254 |
| PDX1258 | USP7-IN-1 | 0.0316 | 1.0633 | -0.01214 |
| PDX1258 | USP7-IN-1 | 0.099927974 | 0.9166 | 0.00091 |
| PDX1258 | USP7-IN-1 | 0.316 | 0.9322 | 0.01859 |
| PDX1258 | USP7-IN-1 | 0.999279741 | 0.8041 | 0.02715 |
| PDX1258 | USP7-IN-1 | 3.16 | 0.9937 | -0.01316 |
| PDX1258 | USP7-IN-1 | 9.992797406 | 0.8993 | 0.00067 |
| PDX1258 | USP7-IN-1 | 31.6 | 0.8316 | 0.02127 |
| PDX1258 | USP7-IN-1 | 50.0 | 0.8007 | 0.02531 |
| PDX1258 | Doxycycline | 0.009992797 | 0.6936 | 0.07621 |
| PDX1258 | Doxycycline | 0.0316 | 1.0236 | -0.00724 |
| PDX1258 | Doxycycline | 0.099927974 | 0.9779 | -0.00853 |
| PDX1258 | Doxycycline | 0.316 | 0.9063 | 0.01957 |
| PDX1258 | Doxycycline | 0.999279741 | 0.8906 | -0.00634 |
| PDX1258 | Doxycycline | 3.16 | 0.8318 | 0.01249 |
| PDX1258 | Doxycycline | 9.992797406 | 0.9153 | 0.01326 |
| PDX1258 | Doxycycline | 31.6 | 0.6556 | 0.01320 |
| PDX1258 | Doxycycline | 50.0 | 0.6311 | 0.04213 |
| PDX1258 | GW7647 | 0.009992797 | 0.9428 | 0.01148 |
| PDX1258 | GW7647 | 0.0316 | 1.0050 | 0.00156 |
| PDX1258 | GW7647 | 0.099927974 | 1.0512 | 0.01150 |
| PDX1258 | GW7647 | 0.316 | 0.9984 | 0.01234 |
| PDX1258 | GW7647 | 0.999279741 | 1.0215 | 0.00260 |
| PDX1258 | GW7647 | 3.16 | 1.1602 | -0.00359 |