Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MDA-MB-361 | z-VAE(OMe)-fmk | 0.0316 | 1.0336 | -0.00600 |
| MDA-MB-361 | z-VAE(OMe)-fmk | 0.099927974 | 0.7902 | -0.00591 |
| MDA-MB-361 | z-VAE(OMe)-fmk | 0.316 | 1.0160 | -0.01032 |
| MDA-MB-361 | z-VAE(OMe)-fmk | 0.999279741 | 1.0995 | -0.01073 |
| MDA-MB-361 | z-VAE(OMe)-fmk | 3.16 | 1.0915 | -0.00482 |
| MDA-MB-361 | z-VAE(OMe)-fmk | 9.992797406 | 0.7647 | 0.00433 |
| MDA-MB-361 | z-VAE(OMe)-fmk | 31.6 | 0.9125 | 0.00744 |
| MDA-MB-361 | z-VAE(OMe)-fmk | 50.0 | 0.9096 | 0.02402 |
| PDX1258 | 1247825-37-1 | 0.009992797 | 1.1668 | -0.01834 |
| PDX1258 | 1247825-37-1 | 0.0316 | 0.9765 | 0.01586 |
| PDX1258 | 1247825-37-1 | 0.099927974 | 1.0410 | -0.00622 |
| PDX1258 | 1247825-37-1 | 0.316 | 1.0416 | -0.00012 |
| PDX1258 | 1247825-37-1 | 0.999279741 | 1.0610 | -0.01526 |
| PDX1258 | 1247825-37-1 | 3.16 | 1.0859 | -0.02737 |
| PDX1258 | 1247825-37-1 | 9.992797406 | 0.7861 | -0.00345 |
| PDX1258 | 1247825-37-1 | 31.6 | 0.1210 | 0.17410 |
| PDX1258 | 1247825-37-1 | 50.0 | 0.1453 | 0.17751 |
| PDX1258 | b-AP15 | 0.009992797 | 1.0167 | 0.00917 |
| PDX1258 | b-AP15 | 0.0316 | 0.9817 | 0.00224 |
| PDX1258 | b-AP15 | 0.099927974 | 0.8127 | 0.06953 |
| PDX1258 | b-AP15 | 0.316 | 0.1462 | 0.30536 |
| PDX1258 | b-AP15 | 0.999279741 | -0.2760 | 0.36448 |
| PDX1258 | b-AP15 | 3.16 | -0.3349 | 0.41698 |
| PDX1258 | b-AP15 | 9.992797406 | -0.5907 | 0.58606 |
| PDX1258 | b-AP15 | 31.6 | -0.6227 | 0.60782 |