Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDX1328 | 1247825-37-1 | 0.999279741 | 1.0800 | 0.00326 |
| PDX1328 | 1247825-37-1 | 3.16 | 1.2900 | 0.00497 |
| PDX1328 | 1247825-37-1 | 9.992797406 | 1.0313 | 0.03126 |
| PDX1328 | 1247825-37-1 | 31.6 | -0.1218 | 0.13251 |
| PDX1328 | 1247825-37-1 | 50.0 | -0.4424 | 0.25128 |
| PDX1328 | b-AP15 | 0.009992797 | 1.0351 | -0.00162 |
| PDX1328 | b-AP15 | 0.0316 | 0.9764 | 0.00073 |
| PDX1328 | b-AP15 | 0.099927974 | 0.8814 | 0.06705 |
| PDX1328 | b-AP15 | 0.316 | -0.1115 | 0.23636 |
| PDX1328 | b-AP15 | 0.999279741 | -0.7780 | 0.42578 |
| PDX1328 | b-AP15 | 3.16 | -0.8782 | 0.42865 |
| PDX1328 | b-AP15 | 9.992797406 | -0.8632 | 0.45776 |
| PDX1328 | b-AP15 | 31.6 | -0.9086 | 0.49260 |
| PDX1328 | b-AP15 | 50.0 | -0.9168 | 0.32912 |
| PDX1328 | USP7-IN-1 | 0.009992797 | 1.0083 | 0.01323 |
| PDX1328 | USP7-IN-1 | 0.0316 | 0.8914 | -0.00014 |
| PDX1328 | USP7-IN-1 | 0.099927974 | 0.8947 | -0.00888 |
| PDX1328 | USP7-IN-1 | 0.316 | 0.8020 | 0.02658 |
| PDX1328 | USP7-IN-1 | 0.999279741 | 0.8765 | 0.02810 |
| PDX1328 | USP7-IN-1 | 3.16 | 1.0049 | 0.00962 |
| PDX1328 | USP7-IN-1 | 9.992797406 | 0.7110 | -0.01150 |
| PDX1328 | USP7-IN-1 | 31.6 | 0.9871 | -0.01439 |
| PDX1328 | USP7-IN-1 | 50.0 | 0.9243 | -0.00530 |
| PDX1328 | Doxycycline | 0.009992797 | 0.5815 | 0.02870 |
| PDX1328 | Doxycycline | 0.0316 | 0.8724 | 0.00286 |