Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| HCC1428 | Dinaciclib | 0.0031623 | pan CDK | Cell cycle | 0.9874 | -0.01140 |
| HCC1428 | Dinaciclib | 0.01 | pan CDK | Cell cycle | 0.8741 | 0.00193 |
| HCC1428 | Dinaciclib | 0.031623 | pan CDK | Cell cycle | -0.2011 | 0.28303 |
| HCC1428 | Dinaciclib | 0.1 | pan CDK | Cell cycle | -0.5503 | 0.56120 |
| HCC1428 | Dinaciclib | 0.31623 | pan CDK | Cell cycle | -0.6189 | 0.64315 |
| HCC1428 | Dinaciclib | 1.0 | pan CDK | Cell cycle | -0.6716 | 0.68657 |
| HCC1428 | Cisplatin | 0.0010833 | Chemo | Chemotherapy | 1.0555 | -0.00577 |
| HCC1428 | Cisplatin | 0.0033333 | Chemo | Chemotherapy | 0.8839 | 0.00009 |
| HCC1428 | Cisplatin | 0.01 | Chemo | Chemotherapy | 1.4076 | -0.00053 |
| HCC1428 | Cisplatin | 0.031667 | Chemo | Chemotherapy | 0.9871 | 0.01022 |
| HCC1428 | Cisplatin | 0.1 | Chemo | Chemotherapy | 0.9402 | 0.01187 |
| HCC1428 | Cisplatin | 0.31623 | Chemo | Chemotherapy | 0.7479 | -0.00691 |
| HCC1428 | Cisplatin | 1.0 | Chemo | Chemotherapy | 0.4984 | 0.01312 |
| HCC1428 | Cisplatin | 3.1623 | Chemo | Chemotherapy | 0.1983 | 0.03469 |
| HCC1428 | Cisplatin | 10.0 | Chemo | Chemotherapy | 0.1223 | 0.02977 |
| HCC1428 | Doxorubicin | 0.00031623 | Chemo | Chemotherapy | 0.9118 | -0.00079 |
| HCC1428 | Doxorubicin | 0.001 | Chemo | Chemotherapy | 0.8928 | 0.00411 |
| HCC1428 | Doxorubicin | 0.0031623 | Chemo | Chemotherapy | 0.5874 | 0.01221 |
| HCC1428 | Doxorubicin | 0.01 | Chemo | Chemotherapy | 0.1252 | 0.04088 |
| HCC1428 | Doxorubicin | 0.031623 | Chemo | Chemotherapy | 0.0737 | 0.09289 |
| HCC1428 | Doxorubicin | 0.1 | Chemo | Chemotherapy | -0.1423 | 0.18388 |
| HCC1428 | Doxorubicin | 0.31623 | Chemo | Chemotherapy | -0.2271 | 0.24291 |
| HCC1428 | Doxorubicin | 1.0 | Chemo | Chemotherapy | -0.5596 | 0.61438 |
| HCC1428 | Doxorubicin | 3.1623 | Chemo | Chemotherapy | -0.7396 | 0.82745 |
| HCC1428 | Taxol | 0.0001 | Chemo | Chemotherapy | 0.7320 | 0.12420 |