Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
HCC1428 | Taxol | 0.00031623 | Chemo | Chemotherapy | 0.9768 | 0.00819 |
HCC1428 | Taxol | 0.001 | Chemo | Chemotherapy | 0.9141 | 0.04839 |
HCC1428 | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.6226 | 0.12420 |
HCC1428 | Taxol | 0.01 | Chemo | Chemotherapy | 0.4539 | 0.32236 |
HCC1428 | Taxol | 0.031623 | Chemo | Chemotherapy | 0.3651 | 0.32836 |
HCC1428 | Taxol | 0.1 | Chemo | Chemotherapy | 0.1145 | 0.31338 |
HCC1428 | Taxol | 0.31623 | Chemo | Chemotherapy | 0.0645 | 0.29204 |
HCC1428 | Taxol | 1.0 | Chemo | Chemotherapy | 0.1391 | 0.27924 |
HCC1428 | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.9152 | -0.00282 |
HCC1428 | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.5195 | -0.00101 |
HCC1428 | Topotecan | 0.01 | Topo I | Chemotherapy | 0.8219 | 0.04880 |
HCC1428 | Topotecan | 0.031667 | Topo I | Chemotherapy | 0.0079 | 0.04095 |
HCC1428 | Topotecan | 0.1 | Topo I | Chemotherapy | 0.0584 | 0.05939 |
HCC1428 | Topotecan | 0.31623 | Topo I | Chemotherapy | -0.0154 | 0.08285 |
HCC1428 | Topotecan | 1.0 | Topo I | Chemotherapy | -0.0347 | 0.18278 |
HCC1428 | Topotecan | 3.1623 | Topo I | Chemotherapy | -0.2670 | 0.35714 |
HCC1428 | Topotecan | 10.0 | Topo I | Chemotherapy | -0.3764 | 0.49642 |
HCC1428 | Etoposide | 0.0010833 | Topo II | Chemotherapy | 1.2065 | 0.00015 |
HCC1428 | Etoposide | 0.0033333 | Topo II | Chemotherapy | 0.9156 | -0.00865 |
HCC1428 | Etoposide | 0.01 | Topo II | Chemotherapy | 1.0382 | 0.00760 |
HCC1428 | Etoposide | 0.031667 | Topo II | Chemotherapy | 1.0571 | 0.02232 |
HCC1428 | Etoposide | 0.1 | Topo II | Chemotherapy | 0.7788 | 0.00751 |
HCC1428 | Etoposide | 0.31623 | Topo II | Chemotherapy | 0.3189 | 0.03425 |
HCC1428 | Etoposide | 1.0 | Topo II | Chemotherapy | 0.1571 | 0.08906 |
HCC1428 | Etoposide | 3.1623 | Topo II | Chemotherapy | 0.0514 | 0.11757 |