Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAMA-1 Dasatinib
0.31623
BCR/ABL
MAPK/nRTK
 0.8473 -0.00767
CAMA-1 Dasatinib
1.0
BCR/ABL
MAPK/nRTK
 0.7975 -0.00687
CAMA-1 Dasatinib
3.1623
BCR/ABL
MAPK/nRTK
 0.7675 -0.00726
CAMA-1 Dasatinib
10.0
BCR/ABL
MAPK/nRTK
 0.6790 -0.00678
CAMA-1 Trametinib
0.0001
MEK
MAPK/nRTK
 0.9917 -0.00222
CAMA-1 Trametinib
0.00031623
MEK
MAPK/nRTK
 1.0109 -0.00344
CAMA-1 Trametinib
0.001
MEK
MAPK/nRTK
 0.9050 -0.00147
CAMA-1 Trametinib
0.0031623
MEK
MAPK/nRTK
 0.9489 -0.00489
CAMA-1 Trametinib
0.01
MEK
MAPK/nRTK
 0.8668 0.00011
CAMA-1 Trametinib
0.031623
MEK
MAPK/nRTK
 0.7842 0.00097
CAMA-1 Trametinib
0.1
MEK
MAPK/nRTK
 0.7104 0.00224
CAMA-1 Trametinib
0.31623
MEK
MAPK/nRTK
 0.6515 0.01234
CAMA-1 Trametinib
1.0
MEK
MAPK/nRTK
 0.5526 0.02417
CAMA-1 Saracatinib
0.001
SRC
MAPK/nRTK
 0.9434 0.00559
CAMA-1 Saracatinib
0.0031623
SRC
MAPK/nRTK
 1.0236 -0.00074
CAMA-1 Saracatinib
0.01
SRC
MAPK/nRTK
 0.9799 0.00197
CAMA-1 Saracatinib
0.031623
SRC
MAPK/nRTK
 1.0850 -0.00584
CAMA-1 Saracatinib
0.1
SRC
MAPK/nRTK
 0.9690 0.00511
CAMA-1 Saracatinib
0.31623
SRC
MAPK/nRTK
 0.9979 -0.00016
CAMA-1 Saracatinib
1.0
SRC
MAPK/nRTK
 0.9700 0.00269
CAMA-1 Saracatinib
3.1623
SRC
MAPK/nRTK
 0.9067 -0.00567
CAMA-1 Saracatinib
10.0
SRC
MAPK/nRTK
 0.7736 -0.00710
CAMA-1 ABT-737
0.001
Bcl2/XL
Misc
 0.9807 0.00074
CAMA-1 ABT-737
0.0031623
Bcl2/XL
Misc
 1.0073 -0.00051
CAMA-1 ABT-737
0.01
Bcl2/XL
Misc
 1.0343 -0.00364