Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
T47D Neratinib
0.31623
EGFR/HER2
RTK
 0.5600 0.00910
T47D Neratinib
1.0
EGFR/HER2
RTK
 0.3976 0.00649
T47D Neratinib
3.1623
EGFR/HER2
RTK
 0.1949 0.02327
T47D Tivantinib
0.001
MET
RTK
 1.1704 0.00007
T47D Tivantinib
0.0031623
MET
RTK
 0.9944 -0.00185
T47D Tivantinib
0.01
MET
RTK
 1.1183 -0.00429
T47D Tivantinib
0.031623
MET
RTK
 1.0430 0.00137
T47D Tivantinib
0.1
MET
RTK
 1.0641 -0.00219
T47D Tivantinib
0.31623
MET
RTK
 0.5916 0.11643
T47D Tivantinib
1.0
MET
RTK
 -0.0899 0.40771
T47D Tivantinib
3.1623
MET
RTK
 -0.1544 0.39446
T47D Tivantinib
10.0
MET
RTK
 -0.1382 0.22895
T47D Cediranib
0.001
VEGFR/cKIT
RTK
 1.0199 -0.00080
T47D Cediranib
0.0031623
VEGFR/cKIT
RTK
 1.0235 0.00154
T47D Cediranib
0.01
VEGFR/cKIT
RTK
 1.0474 -0.00177
T47D Cediranib
0.031623
VEGFR/cKIT
RTK
 1.0481 -0.00119
T47D Cediranib
0.1
VEGFR/cKIT
RTK
 1.0717 0.00087
T47D Cediranib
0.31623
VEGFR/cKIT
RTK
 0.9776 -0.00031
T47D Cediranib
1.0
VEGFR/cKIT
RTK
 0.9308 0.00485
T47D Cediranib
3.1623
VEGFR/cKIT
RTK
 0.7362 0.00772
T47D Cediranib
10.0
VEGFR/cKIT
RTK
 -0.6403 0.66759
T47D Cabozantinib
0.001
VEGFR2/MET
RTK
 1.0327 0.00168
T47D Cabozantinib
0.0031623
VEGFR2/MET
RTK
 1.0074 -0.00117
T47D Cabozantinib
0.01
VEGFR2/MET
RTK
 0.9974 0.00113
T47D Cabozantinib
0.031623
VEGFR2/MET
RTK
 0.9902 0.00410