Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MCF 10A Taxol
0.0001
Chemo
Chemotherapy
 0.9571 0.00191
MCF 10A Taxol
0.00031623
Chemo
Chemotherapy
 0.9994 0.00273
MCF 10A Taxol
0.001
Chemo
Chemotherapy
 0.9039 0.01074
MCF 10A Taxol
0.0031623
Chemo
Chemotherapy
 0.3848 0.17847
MCF 10A Taxol
0.01
Chemo
Chemotherapy
 0.0381 0.38434
MCF 10A Taxol
0.031623
Chemo
Chemotherapy
 -0.0992 0.43459
MCF 10A Taxol
0.1
Chemo
Chemotherapy
 -0.1416 0.46301
MCF 10A Taxol
0.31623
Chemo
Chemotherapy
 -0.1200 0.43155
MCF 10A Taxol
1.0
Chemo
Chemotherapy
 -0.1256 0.41097
MCF 10A Topotecan
0.0010833
Topo I
Chemotherapy
 0.9471 -0.00314
MCF 10A Topotecan
0.0033333
Topo I
Chemotherapy
 0.8089 0.00699
MCF 10A Topotecan
0.01
Topo I
Chemotherapy
 0.4902 0.09016
MCF 10A Topotecan
0.031667
Topo I
Chemotherapy
 0.1153 0.11044
MCF 10A Topotecan
0.1
Topo I
Chemotherapy
 0.1191 0.09659
MCF 10A Topotecan
0.31623
Topo I
Chemotherapy
 0.0692 0.11744
MCF 10A Topotecan
1.0
Topo I
Chemotherapy
 0.0183 0.16334
MCF 10A Topotecan
3.1623
Topo I
Chemotherapy
 -0.0828 0.28763
MCF 10A Topotecan
10.0
Topo I
Chemotherapy
 -0.2000 0.39149
MCF 10A Etoposide
0.0010833
Topo II
Chemotherapy
 0.9963 -0.00060
MCF 10A Etoposide
0.0033333
Topo II
Chemotherapy
 0.9832 -0.00304
MCF 10A Etoposide
0.01
Topo II
Chemotherapy
 0.9613 0.00178
MCF 10A Etoposide
0.031667
Topo II
Chemotherapy
 0.9449 0.00104
MCF 10A Etoposide
0.1
Topo II
Chemotherapy
 0.7959 0.01287
MCF 10A Etoposide
0.31623
Topo II
Chemotherapy
 0.4931 0.09570
MCF 10A Etoposide
1.0
Topo II
Chemotherapy
 0.0677 0.17013