Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
Hs 578T ABT-737
0.01
Bcl2/XL
Misc
 1.0474 0.00553
Hs 578T ABT-737
0.031623
Bcl2/XL
Misc
 0.9864 0.00605
Hs 578T ABT-737
0.1
Bcl2/XL
Misc
 1.0131 0.01031
Hs 578T ABT-737
0.31623
Bcl2/XL
Misc
 0.9967 0.00856
Hs 578T ABT-737
1.0
Bcl2/XL
Misc
 0.9567 0.02010
Hs 578T ABT-737
3.1623
Bcl2/XL
Misc
 0.8838 0.03824
Hs 578T ABT-737
10.0
Bcl2/XL
Misc
 0.7755 0.06816
Hs 578T Vorinostat
0.001
HDAC
Misc
 1.0117 0.00084
Hs 578T Vorinostat
0.0031623
HDAC
Misc
 0.9668 -0.00319
Hs 578T Vorinostat
0.01
HDAC
Misc
 1.0665 -0.00223
Hs 578T Vorinostat
0.031623
HDAC
Misc
 1.0296 0.00131
Hs 578T Vorinostat
0.1
HDAC
Misc
 1.0643 -0.00098
Hs 578T Vorinostat
0.31623
HDAC
Misc
 0.9301 0.00606
Hs 578T Vorinostat
1.0
HDAC
Misc
 0.4258 0.10793
Hs 578T Vorinostat
3.1623
HDAC
Misc
 -0.0561 0.35835
Hs 578T Vorinostat
10.0
HDAC
Misc
 -0.1689 0.47589
Hs 578T Luminespib
0.0001
HSP90
Misc
 0.9779 0.00503
Hs 578T Luminespib
0.00031623
HSP90
Misc
 0.9945 -0.00103
Hs 578T Luminespib
0.001
HSP90
Misc
 1.0057 0.00126
Hs 578T Luminespib
0.0031623
HSP90
Misc
 0.5157 0.10357
Hs 578T Luminespib
0.01
HSP90
Misc
 -0.0019 0.36018
Hs 578T Luminespib
0.031623
HSP90
Misc
 -0.1005 0.39767
Hs 578T Luminespib
0.1
HSP90
Misc
 -0.1013 0.39406
Hs 578T Luminespib
0.31623
HSP90
Misc
 -0.1029 0.38298
Hs 578T Luminespib
1.0
HSP90
Misc
 -0.1144 0.41607