Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
Hs 578T Dinaciclib
1.0
pan CDK
Cell cycle
 -0.2388 0.43506
Hs 578T Cisplatin
0.0010833
Chemo
Chemotherapy
 1.0006 0.00041
Hs 578T Cisplatin
0.0033333
Chemo
Chemotherapy
 0.9561 0.00052
Hs 578T Cisplatin
0.01
Chemo
Chemotherapy
 0.9522 0.00122
Hs 578T Cisplatin
0.031667
Chemo
Chemotherapy
 0.9790 -0.00069
Hs 578T Cisplatin
0.1
Chemo
Chemotherapy
 0.9507 0.00042
Hs 578T Cisplatin
0.31623
Chemo
Chemotherapy
 0.8896 0.01779
Hs 578T Cisplatin
1.0
Chemo
Chemotherapy
 0.6854 0.09785
Hs 578T Cisplatin
3.1623
Chemo
Chemotherapy
 0.2165 0.35450
Hs 578T Cisplatin
10.0
Chemo
Chemotherapy
 0.0125 0.36491
Hs 578T Doxorubicin
0.00031623
Chemo
Chemotherapy
 0.9514 0.00129
Hs 578T Doxorubicin
0.001
Chemo
Chemotherapy
 0.9053 0.01728
Hs 578T Doxorubicin
0.0031623
Chemo
Chemotherapy
 0.6139 0.11735
Hs 578T Doxorubicin
0.01
Chemo
Chemotherapy
 0.1026 0.34106
Hs 578T Doxorubicin
0.031623
Chemo
Chemotherapy
 0.0095 0.19791
Hs 578T Doxorubicin
0.1
Chemo
Chemotherapy
 -0.0372 0.22098
Hs 578T Doxorubicin
0.31623
Chemo
Chemotherapy
 -0.1066 0.30798
Hs 578T Doxorubicin
1.0
Chemo
Chemotherapy
 -0.1953 0.39971
Hs 578T Doxorubicin
3.1623
Chemo
Chemotherapy
 -0.3466 0.60172
Hs 578T Taxol
0.0001
Chemo
Chemotherapy
 0.6739 0.08314
Hs 578T Taxol
0.00031623
Chemo
Chemotherapy
 0.9477 0.03143
Hs 578T Taxol
0.001
Chemo
Chemotherapy
 0.5186 0.25154
Hs 578T Taxol
0.0031623
Chemo
Chemotherapy
 0.0076 0.46628
Hs 578T Taxol
0.01
Chemo
Chemotherapy
 -0.2629 0.63221
Hs 578T Taxol
0.031623
Chemo
Chemotherapy
 -0.2867 0.66509