Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
Hs 578T Taxol
0.1
Chemo
Chemotherapy
 -0.3681 0.72674
Hs 578T Taxol
0.31623
Chemo
Chemotherapy
 -0.3332 0.70271
Hs 578T Taxol
1.0
Chemo
Chemotherapy
 -0.3752 0.74970
Hs 578T Topotecan
0.0010833
Topo I
Chemotherapy
 0.9689 0.00334
Hs 578T Topotecan
0.0033333
Topo I
Chemotherapy
 0.7199 0.07355
Hs 578T Topotecan
0.01
Topo I
Chemotherapy
 0.0439 0.42958
Hs 578T Topotecan
0.031667
Topo I
Chemotherapy
 -0.0071 0.39115
Hs 578T Topotecan
0.1
Topo I
Chemotherapy
 -0.1242 0.47474
Hs 578T Topotecan
0.31623
Topo I
Chemotherapy
 -0.2287 0.59734
Hs 578T Topotecan
1.0
Topo I
Chemotherapy
 -0.3337 0.69467
Hs 578T Topotecan
3.1623
Topo I
Chemotherapy
 -0.4314 0.78405
Hs 578T Topotecan
10.0
Topo I
Chemotherapy
 -0.4488 0.79649
Hs 578T Etoposide
0.0010833
Topo II
Chemotherapy
 1.0257 0.00293
Hs 578T Etoposide
0.0033333
Topo II
Chemotherapy
 1.0092 -0.00370
Hs 578T Etoposide
0.01
Topo II
Chemotherapy
 0.9941 -0.00216
Hs 578T Etoposide
0.031667
Topo II
Chemotherapy
 1.0041 0.00180
Hs 578T Etoposide
0.1
Topo II
Chemotherapy
 0.9312 0.01527
Hs 578T Etoposide
0.31623
Topo II
Chemotherapy
 0.6522 0.12890
Hs 578T Etoposide
1.0
Topo II
Chemotherapy
 0.0578 0.43655
Hs 578T Etoposide
3.1623
Topo II
Chemotherapy
 -0.0824 0.46428
Hs 578T Etoposide
10.0
Topo II
Chemotherapy
 -0.1361 0.45511
Hs 578T Dasatinib
0.001
BCR/ABL
MAPK/nRTK
 0.9022 -0.00534
Hs 578T Dasatinib
0.0031623
BCR/ABL
MAPK/nRTK
 0.8311 0.00352
Hs 578T Dasatinib
0.01
BCR/ABL
MAPK/nRTK
 0.8314 -0.00124
Hs 578T Dasatinib
0.031623
BCR/ABL
MAPK/nRTK
 0.6216 0.04263