Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1806 ABT-737
10.0
Bcl2/XL
Misc
 0.7293 0.12622
HCC1806 Vorinostat
0.001
HDAC
Misc
 1.0136 -0.00693
HCC1806 Vorinostat
0.0031623
HDAC
Misc
 1.0396 -0.00386
HCC1806 Vorinostat
0.01
HDAC
Misc
 1.0312 -0.00004
HCC1806 Vorinostat
0.031623
HDAC
Misc
 1.0082 -0.00167
HCC1806 Vorinostat
0.1
HDAC
Misc
 0.9246 0.00705
HCC1806 Vorinostat
0.31623
HDAC
Misc
 0.8452 0.01588
HCC1806 Vorinostat
1.0
HDAC
Misc
 0.5599 0.05417
HCC1806 Vorinostat
3.1623
HDAC
Misc
 0.1581 0.17812
HCC1806 Vorinostat
10.0
HDAC
Misc
 0.0178 0.19873
HCC1806 Luminespib
0.0001
HSP90
Misc
 1.0518 -0.00289
HCC1806 Luminespib
0.00031623
HSP90
Misc
 0.9805 0.00293
HCC1806 Luminespib
0.001
HSP90
Misc
 1.0670 -0.00065
HCC1806 Luminespib
0.0031623
HSP90
Misc
 1.0288 -0.00478
HCC1806 Luminespib
0.01
HSP90
Misc
 0.5586 0.11289
HCC1806 Luminespib
0.031623
HSP90
Misc
 -0.0692 0.36562
HCC1806 Luminespib
0.1
HSP90
Misc
 -0.1502 0.44524
HCC1806 Luminespib
0.31623
HSP90
Misc
 -0.1663 0.45752
HCC1806 Luminespib
1.0
HSP90
Misc
 -0.1751 0.47227
HCC1806 A-1210477
0.001
Mcl-1
Misc
 0.9844 -0.00747
HCC1806 A-1210477
0.0031623
Mcl-1
Misc
 1.0324 -0.00234
HCC1806 A-1210477
0.01
Mcl-1
Misc
 0.9898 0.00630
HCC1806 A-1210477
0.031623
Mcl-1
Misc
 0.9977 0.00363
HCC1806 A-1210477
0.1
Mcl-1
Misc
 0.9950 0.00255
HCC1806 A-1210477
0.31623
Mcl-1
Misc
 1.0678 -0.00565