Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1806 A-1210477
1.0
Mcl-1
Misc
 1.0685 0.00202
HCC1806 A-1210477
3.1623
Mcl-1
Misc
 1.0029 -0.00692
HCC1806 A-1210477
10.0
Mcl-1
Misc
 0.9047 0.02127
HCC1806 Olaparib
0.001
PARP
Misc
 0.9723 0.00706
HCC1806 Olaparib
0.0031623
PARP
Misc
 0.9575 0.01003
HCC1806 Olaparib
0.01
PARP
Misc
 0.9903 0.00626
HCC1806 Olaparib
0.031623
PARP
Misc
 0.9928 0.00514
HCC1806 Olaparib
0.1
PARP
Misc
 0.9821 0.00980
HCC1806 Olaparib
0.31623
PARP
Misc
 0.8612 0.01429
HCC1806 Olaparib
1.0
PARP
Misc
 0.9054 0.01713
HCC1806 Olaparib
3.1623
PARP
Misc
 0.8180 0.02674
HCC1806 Olaparib
10.0
PARP
Misc
 0.4886 0.10512
HCC1806 Bleomycin
0.0010833
Radiation
Misc
 1.0353 -0.00052
HCC1806 Bleomycin
0.0033333
Radiation
Misc
 1.0827 0.00123
HCC1806 Bleomycin
0.01
Radiation
Misc
 0.9790 0.00847
HCC1806 Bleomycin
0.031667
Radiation
Misc
 0.9767 0.01401
HCC1806 Bleomycin
0.1
Radiation
Misc
 1.0283 0.00115
HCC1806 Bleomycin
0.31623
Radiation
Misc
 0.8449 0.01614
HCC1806 Bleomycin
1.0
Radiation
Misc
 0.7704 0.03520
HCC1806 Bleomycin
3.1623
Radiation
Misc
 0.6374 0.05149
HCC1806 Bleomycin
10.0
Radiation
Misc
 0.4813 0.10036
HCC1806 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9472 -0.00031
HCC1806 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0171 -0.00556
HCC1806 Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9750 0.00451
HCC1806 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9999 -0.00551