Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1806 Trametinib
0.00031623
MEK
MAPK/nRTK
 1.0766 -0.00142
HCC1806 Trametinib
0.001
MEK
MAPK/nRTK
 1.0631 0.00977
HCC1806 Trametinib
0.0031623
MEK
MAPK/nRTK
 1.0012 0.01922
HCC1806 Trametinib
0.01
MEK
MAPK/nRTK
 0.8218 0.03053
HCC1806 Trametinib
0.031623
MEK
MAPK/nRTK
 0.8318 0.04358
HCC1806 Trametinib
0.1
MEK
MAPK/nRTK
 0.7512 0.04449
HCC1806 Trametinib
0.31623
MEK
MAPK/nRTK
 0.7036 0.06176
HCC1806 Trametinib
1.0
MEK
MAPK/nRTK
 0.8139 0.03787
HCC1806 Saracatinib
0.001
SRC
MAPK/nRTK
 1.0566 -0.00099
HCC1806 Saracatinib
0.0031623
SRC
MAPK/nRTK
 0.9414 0.00576
HCC1806 Saracatinib
0.01
SRC
MAPK/nRTK
 0.9979 0.00123
HCC1806 Saracatinib
0.031623
SRC
MAPK/nRTK
 0.9628 0.01339
HCC1806 Saracatinib
0.1
SRC
MAPK/nRTK
 0.8122 0.03066
HCC1806 Saracatinib
0.31623
SRC
MAPK/nRTK
 0.8002 0.05058
HCC1806 Saracatinib
1.0
SRC
MAPK/nRTK
 0.5483 0.07837
HCC1806 Saracatinib
3.1623
SRC
MAPK/nRTK
 0.4325 0.11326
HCC1806 Saracatinib
10.0
SRC
MAPK/nRTK
 0.2213 0.14013
HCC1806 ABT-737
0.001
Bcl2/XL
Misc
 1.0427 -0.00094
HCC1806 ABT-737
0.0031623
Bcl2/XL
Misc
 1.0420 0.00490
HCC1806 ABT-737
0.01
Bcl2/XL
Misc
 1.0592 -0.00309
HCC1806 ABT-737
0.031623
Bcl2/XL
Misc
 1.0731 -0.00052
HCC1806 ABT-737
0.1
Bcl2/XL
Misc
 1.1723 -0.00198
HCC1806 ABT-737
0.31623
Bcl2/XL
Misc
 1.2119 -0.00429
HCC1806 ABT-737
1.0
Bcl2/XL
Misc
 1.2575 -0.00552
HCC1806 ABT-737
3.1623
Bcl2/XL
Misc
 1.1888 0.00960