Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
Hs 578T Cediranib
1.0
VEGFR/cKIT
RTK
 0.3858 0.10669
Hs 578T Cediranib
3.1623
VEGFR/cKIT
RTK
 0.1560 0.19759
Hs 578T Cediranib
10.0
VEGFR/cKIT
RTK
 -0.5723 0.81093
Hs 578T Cabozantinib
0.001
VEGFR2/MET
RTK
 0.9230 0.00275
Hs 578T Cabozantinib
0.0031623
VEGFR2/MET
RTK
 0.9803 0.00051
Hs 578T Cabozantinib
0.01
VEGFR2/MET
RTK
 0.9360 0.01111
Hs 578T Cabozantinib
0.031623
VEGFR2/MET
RTK
 0.9663 0.01046
Hs 578T Cabozantinib
0.1
VEGFR2/MET
RTK
 0.8875 0.02037
Hs 578T Cabozantinib
0.31623
VEGFR2/MET
RTK
 0.9045 0.01765
Hs 578T Cabozantinib
1.0
VEGFR2/MET
RTK
 0.8396 0.02688
Hs 578T Cabozantinib
3.1623
VEGFR2/MET
RTK
 0.8488 0.03305
Hs 578T Cabozantinib
10.0
VEGFR2/MET
RTK
 0.2155 0.28407
MCF 10A Abemaciclib
0.001
CDK4/6
Cell cycle
 0.9861 -0.00068
MCF 10A Abemaciclib
0.0031623
CDK4/6
Cell cycle
 0.9496 -0.00332
MCF 10A Abemaciclib
0.01
CDK4/6
Cell cycle
 0.8774 -0.00666
MCF 10A Abemaciclib
0.031623
CDK4/6
Cell cycle
 0.7684 -0.00888
MCF 10A Abemaciclib
0.1
CDK4/6
Cell cycle
 0.6529 -0.00823
MCF 10A Abemaciclib
0.31623
CDK4/6
Cell cycle
 0.5264 -0.00795
MCF 10A Abemaciclib
1.0
CDK4/6
Cell cycle
 0.3536 -0.00320
MCF 10A Abemaciclib
3.1623
CDK4/6
Cell cycle
 0.2543 -0.00150
MCF 10A Abemaciclib
10.0
CDK4/6
Cell cycle
 0.1513 0.02969
MCF 10A Palbociclib
0.00031623
CDK4/6
Cell cycle
 1.0029 0.00075
MCF 10A Palbociclib
0.001
CDK4/6
Cell cycle
 1.0040 0.00068
MCF 10A Palbociclib
0.0031623
CDK4/6
Cell cycle
 0.9789 -0.00222
MCF 10A Palbociclib
0.01
CDK4/6
Cell cycle
 0.9387 -0.00416