Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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| Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MZ7-mel | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 1 | 2184 | 178 | 0.6360 | 0.3928 | 0.0815 | 0.0863 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 2 | 1323 | 115 | 0.3830 | 0.3928 | 0.0869 | 0.0863 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 3 | 553 | 50 | 0.1595 | 0.3928 | 0.0904 | 0.0863 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 1 | 1655 | 235 | 0.4502 | 0.3276 | 0.1420 | 0.1373 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 2 | 1344 | 172 | 0.3716 | 0.3276 | 0.1280 | 0.1373 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 3 | 592 | 84 | 0.1611 | 0.3276 | 0.1419 | 0.1373 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 1 | 1154 | 182 | 0.3082 | 0.4353 | 0.1577 | 0.1651 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 2 | 1678 | 311 | 0.4334 | 0.4353 | 0.1853 | 0.1651 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 3 | 2100 | 320 | 0.5644 | 0.4353 | 0.1524 | 0.1651 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 1 | 1156 | 177 | 0.3104 | 0.2894 | 0.1531 | 0.1571 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 2 | 960 | 143 | 0.2590 | 0.2894 | 0.1490 | 0.1571 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 3 | 1134 | 192 | 0.2987 | 0.2894 | 0.1693 | 0.1571 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 1 | 1778 | 308 | 0.4661 | 0.3116 | 0.1732 | 0.1548 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 2 | 1274 | 191 | 0.3434 | 0.3116 | 0.1499 | 0.1548 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 3 | 460 | 65 | 0.1252 | 0.3116 | 0.1413 | 0.1548 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 1 | 937 | 165 | 0.2448 | 0.2060 | 0.1761 | 0.1979 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 2 | 895 | 190 | 0.2235 | 0.2060 | 0.2123 | 0.1979 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 3 | 594 | 122 | 0.1497 | 0.2060 | 0.2054 | 0.1979 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 1 | 1092 | 349 | 0.2356 | 0.3216 | 0.3196 | 0.3331 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 2 | 1571 | 537 | 0.3278 | 0.3216 | 0.3418 | 0.3331 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 3 | 1912 | 646 | 0.4014 | 0.3216 | 0.3379 | 0.3331 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 1 | 630 | 162 | 0.1484 | 0.1384 | 0.2571 | 0.2350 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 2 | 532 | 117 | 0.1316 | 0.1384 | 0.2199 | 0.2350 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 3 | 553 | 126 | 0.1354 | 0.1384 | 0.2278 | 0.2350 |
| MZ7-mel | Vemurafenib | JNK-IN-8 | 3.160 | 1.000 | uM | 72 | hr | 1 | 1742 | 515 | 0.3890 | 0.2359 | 0.2956 | 0.2994 |