Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MZ7-mel Vemurafenib JNK-IN-8 3.160 1.000
uM
 72
hr
 2 955 306 0.2058 0.2359 0.3204 0.2994
MZ7-mel Vemurafenib JNK-IN-8 3.160 1.000
uM
 72
hr
 3 496 140 0.1129 0.2359 0.2823 0.2994
MZ7-mel Vemurafenib JNK-IN-8 3.160 3.160
uM
 72
hr
 1 526 138 0.1230 0.1027 0.2624 0.2808
MZ7-mel Vemurafenib JNK-IN-8 3.160 3.160
uM
 72
hr
 2 446 136 0.0983 0.1027 0.3049 0.2808
MZ7-mel Vemurafenib JNK-IN-8 3.160 3.160
uM
 72
hr
 3 378 104 0.0869 0.1027 0.2751 0.2808
MZ7-mel Vemurafenib PF562271 0.000 0.000
uM
 72
hr
 1 3528 190 0.9630 1.0000 0.0539 0.0545
MZ7-mel Vemurafenib PF562271 0.000 0.000
uM
 72
hr
 2 3736 214 1.0161 1.0000 0.0573 0.0545
MZ7-mel Vemurafenib PF562271 0.000 0.000
uM
 72
hr
 3 3734 195 1.0210 1.0000 0.0522 0.0545
MZ7-mel Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 1 4085 262 1.1029 1.3927 0.0641 0.0616
MZ7-mel Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 2 5640 348 1.5267 1.3927 0.0617 0.0616
MZ7-mel Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 3 5704 336 1.5486 1.3927 0.0589 0.0616
MZ7-mel Vemurafenib PF562271 0.000 1.000
uM
 72
hr
 1 3148 195 0.8519 0.7323 0.0619 0.0602
MZ7-mel Vemurafenib PF562271 0.000 1.000
uM
 72
hr
 2 2823 172 0.7648 0.7323 0.0609 0.0602
MZ7-mel Vemurafenib PF562271 0.000 1.000
uM
 72
hr
 3 2134 123 0.5802 0.7323 0.0576 0.0602
MZ7-mel Vemurafenib PF562271 0.000 3.160
uM
 72
hr
 1 2113 106 0.5790 0.4111 0.0502 0.0604
MZ7-mel Vemurafenib PF562271 0.000 3.160
uM
 72
hr
 2 1525 91 0.4137 0.4111 0.0597 0.0604
MZ7-mel Vemurafenib PF562271 0.000 3.160
uM
 72
hr
 3 898 64 0.2406 0.4111 0.0713 0.0604
MZ7-mel Vemurafenib PF562271 0.100 0.000
uM
 72
hr
 1 2050 110 0.5597 0.6853 0.0537 0.0479
MZ7-mel Vemurafenib PF562271 0.100 0.000
uM
 72
hr
 2 2653 123 0.7299 0.6853 0.0464 0.0479
MZ7-mel Vemurafenib PF562271 0.100 0.000
uM
 72
hr
 3 2777 121 0.7662 0.6853 0.0436 0.0479
MZ7-mel Vemurafenib PF562271 0.100 0.316
uM
 72
hr
 1 2852 143 0.7815 0.9528 0.0501 0.0436
MZ7-mel Vemurafenib PF562271 0.100 0.316
uM
 72
hr
 2 3775 147 1.0466 0.9528 0.0389 0.0436
MZ7-mel Vemurafenib PF562271 0.100 0.316
uM
 72
hr
 3 3726 155 1.0302 0.9528 0.0416 0.0436
MZ7-mel Vemurafenib PF562271 0.100 1.000
uM
 72
hr
 1 2768 138 0.7587 0.6073 0.0499 0.0523
MZ7-mel Vemurafenib PF562271 0.100 1.000
uM
 72
hr
 2 2344 121 0.6413 0.6073 0.0516 0.0523