Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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| Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WM-115 | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 1 | 2742 | 343 | 0.6068 | 0.5740 | 0.1251 | 0.1116 |
| WM-115 | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 2 | 2576 | 242 | 0.5903 | 0.5740 | 0.0939 | 0.1116 |
| WM-115 | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 3 | 2347 | 272 | 0.5248 | 0.5740 | 0.1159 | 0.1116 |
| WM-115 | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 1 | 2217 | 585 | 0.4128 | 0.3996 | 0.2639 | 0.2568 |
| WM-115 | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 2 | 2164 | 556 | 0.4067 | 0.3996 | 0.2569 | 0.2568 |
| WM-115 | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 3 | 1999 | 499 | 0.3794 | 0.3996 | 0.2496 | 0.2568 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 1 | 2426 | 337 | 0.5284 | 0.5279 | 0.1389 | 0.1378 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 2 | 2371 | 319 | 0.5190 | 0.5279 | 0.1345 | 0.1378 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 3 | 2466 | 345 | 0.5365 | 0.5279 | 0.1399 | 0.1378 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 1 | 2210 | 349 | 0.4707 | 0.4758 | 0.1579 | 0.1613 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 2 | 2273 | 383 | 0.4780 | 0.4758 | 0.1685 | 0.1613 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 3 | 2246 | 354 | 0.4785 | 0.4758 | 0.1576 | 0.1613 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 1 | 2349 | 487 | 0.4710 | 0.4497 | 0.2073 | 0.2046 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 2 | 2238 | 445 | 0.4535 | 0.4497 | 0.1988 | 0.2046 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 3 | 2119 | 440 | 0.4247 | 0.4497 | 0.2076 | 0.2046 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 1 | 1801 | 675 | 0.2848 | 0.2705 | 0.3748 | 0.4169 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 2 | 1864 | 831 | 0.2613 | 0.2705 | 0.4458 | 0.4169 |
| WM-115 | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 3 | 1841 | 792 | 0.2653 | 0.2705 | 0.4302 | 0.4169 |
| WM-115 | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 1 | 2031 | 480 | 0.3923 | 0.3842 | 0.2363 | 0.2355 |
| WM-115 | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 2 | 1942 | 457 | 0.3756 | 0.3842 | 0.2353 | 0.2355 |
| WM-115 | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 3 | 1988 | 467 | 0.3847 | 0.3842 | 0.2349 | 0.2355 |
| WM-115 | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 1 | 1731 | 422 | 0.3311 | 0.3217 | 0.2438 | 0.2378 |
| WM-115 | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 2 | 1718 | 394 | 0.3349 | 0.3217 | 0.2293 | 0.2378 |
| WM-115 | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 3 | 1557 | 374 | 0.2992 | 0.3217 | 0.2402 | 0.2378 |
| WM-115 | Vemurafenib | JNK-IN-8 | 3.160 | 1.000 | uM | 72 | hr | 1 | 1808 | 599 | 0.3058 | 0.3012 | 0.3313 | 0.3083 |