Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
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COLO 858 | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 1 | 8526 | 1292 | 1.0334 | 1.0000 | 0.1515 | 0.1514 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 2 | 8309 | 1285 | 1.0034 | 1.0000 | 0.1547 | 0.1514 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 3 | 7914 | 1171 | 0.9632 | 1.0000 | 0.1480 | 0.1514 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 0.316 | uM | 72 | hr | 1 | 2057 | 547 | 0.2157 | 0.2671 | 0.2659 | 0.2394 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 0.316 | uM | 72 | hr | 2 | 2337 | 557 | 0.2543 | 0.2671 | 0.2383 | 0.2394 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 0.316 | uM | 72 | hr | 3 | 2951 | 631 | 0.3314 | 0.2671 | 0.2138 | 0.2394 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 1.000 | uM | 72 | hr | 1 | 2340 | 481 | 0.2656 | 0.2433 | 0.2056 | 0.1994 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 1.000 | uM | 72 | hr | 2 | 1951 | 375 | 0.2251 | 0.2433 | 0.1922 | 0.1994 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 1.000 | uM | 72 | hr | 3 | 2094 | 420 | 0.2391 | 0.2433 | 0.2006 | 0.1994 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 3.160 | uM | 72 | hr | 1 | 2868 | 448 | 0.3457 | 0.3076 | 0.1562 | 0.1502 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 3.160 | uM | 72 | hr | 2 | 2387 | 406 | 0.2830 | 0.3076 | 0.1701 | 0.1502 |
COLO 858 | Vemurafenib | Dasatinib | 0.000 | 3.160 | uM | 72 | hr | 3 | 2351 | 292 | 0.2941 | 0.3076 | 0.1242 | 0.1502 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 0.000 | uM | 72 | hr | 1 | 3752 | 367 | 0.4835 | 0.4885 | 0.0978 | 0.0896 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 0.000 | uM | 72 | hr | 2 | 3991 | 355 | 0.5194 | 0.4885 | 0.0890 | 0.0896 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 0.000 | uM | 72 | hr | 3 | 3526 | 289 | 0.4624 | 0.4885 | 0.0820 | 0.0896 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 0.316 | uM | 72 | hr | 1 | 1513 | 641 | 0.1246 | 0.1453 | 0.4237 | 0.3955 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 0.316 | uM | 72 | hr | 2 | 1738 | 710 | 0.1469 | 0.1453 | 0.4085 | 0.3955 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 0.316 | uM | 72 | hr | 3 | 1783 | 632 | 0.1644 | 0.1453 | 0.3545 | 0.3955 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 1.000 | uM | 72 | hr | 1 | 1685 | 555 | 0.1614 | 0.1480 | 0.3294 | 0.3294 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 1.000 | uM | 72 | hr | 2 | 1576 | 517 | 0.1513 | 0.1480 | 0.3280 | 0.3294 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 1.000 | uM | 72 | hr | 3 | 1375 | 455 | 0.1314 | 0.1480 | 0.3309 | 0.3294 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 3.160 | uM | 72 | hr | 1 | 1844 | 660 | 0.1691 | 0.1486 | 0.3579 | 0.3478 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 3.160 | uM | 72 | hr | 2 | 1434 | 506 | 0.1326 | 0.1486 | 0.3529 | 0.3478 |
COLO 858 | Vemurafenib | Dasatinib | 0.100 | 3.160 | uM | 72 | hr | 3 | 1512 | 503 | 0.1441 | 0.1486 | 0.3327 | 0.3478 |
COLO 858 | Vemurafenib | Dasatinib | 0.316 | 0.000 | uM | 72 | hr | 1 | 2454 | 395 | 0.2941 | 0.3034 | 0.1610 | 0.1673 |