Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset (ID:20269)

Download: Excel (XLSX), Comma-separated (CSV)

<<<<

Select the entities to show:

Small molecules	Cells	Antibodies

|<
<<
Previous
Page 209 of 370
Next
>>
>
5201 to 5225 of 9248 records
per page:

Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Biological Replicate ID	Conc Unit	GR50	GEC50	GRmax	GRinf	GR Hill Coefficient	GR_AOC	GR r2	Nominal Division Rate
MCF12A	NM	Basal B	MG-132	Proteasome	Proteasome	14637.189	uM	0.11037	0.17532	-0.7161	-0.6953	1.8833	0.8051	0.9950	2.7087
MCF12A	NM	Basal B	MG-132	Proteasome	Proteasome	14637.189	uM	0.11037	0.17532	-0.7161	-0.6953	1.8833	0.8051	0.9950	2.7087
MCF12A	NM	Basal B	Pevonedistat	NAE1	NAE1	10817.148	uM	0.14985	0.18495	-0.1325	-0.1078	0.9277	0.5159	0.9931	1.4678
MCF12A	NM	Basal B	Pevonedistat	NAE1	NAE1	12365.135	uM	0.08422	0.13514	-0.1925	-0.2002	0.7120	0.5774	0.9984	2.2181
MCF12A	NM	Basal B	Nelfinavir			12949.174	uM	25.91070	85.74380	0.3987	-1.0000	0.9180	0.0971	0.8818	1.9016
MCF12A	NM	Basal B	Nilotinib	ABL	nRTK	12365.17	uM	inf	inf	0.9251	0.9251	0.0000	0.0829	0.0001	2.2930
MCF12A	NM	Basal B	Nilotinib	ABL	nRTK	10817.145	uM	inf	inf	0.9556	0.9556	0.0000	0.0393	0.0596	1.5564
MCF12A	NM	Basal B	NSC 663284	CDC25	CDC	12365.152	uM	1.51110	1.90740	-0.7800	-0.7697	4.0016	0.5870	0.9989	2.1145
MCF12A	NM	Basal B	NSC 663284	CDC25	CDC	10817.152	uM	1.76390	2.17280	-0.9192	-0.9178	5.0000	0.6268	0.9993	1.4414
MCF12A	NM	Basal B	NU6102	CDK1/2	CDK	12365.147	uM	37.52320	46.74370	-0.7116	-1.0000	5.0000	0.1111	0.9860	1.8376
MCF12A	NM	Basal B	NU6102	CDK1/2	CDK	10817.147	uM	12.38750	21.66580	-0.8077	-1.0000	1.9652	0.1993	0.9964	1.5041
MCF12A	NM	Basal B	Nutlin 3a	MDM2	MDM2	7489.066	uM	2.57910	4.46420	-0.0914	-0.2223	0.6704	0.2680	0.9796	2.3124
MCF12A	NM	Basal B	Nutlin 3a	MDM2	MDM2	7490.066	uM	2.42340	2.62270	-0.0111	-0.0365	0.8925	0.2709	0.9866	2.4829
MCF12A	NM	Basal B	Olomoucine II	CDK1	CDK	12365.147	uM	8.70190	10.17430	-0.5590	-0.5590	4.8005	0.2834	0.9939	1.8376
MCF12A	NM	Basal B	Olomoucine II	CDK1	CDK	10817.147	uM	6.10080	6.65030	-0.2731	-0.2694	4.9969	0.2834	0.9975	1.5041
MCF12A	NM	Basal B	Omipalisib	PI3K	PI3K	7490.086	uM	0.01443	0.04565	-0.5016	-0.4446	0.5525	0.7296	0.9879	2.4876
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	10061.12	uM	4.1260	26.98840	-0.7649	-1.0000	0.5850	0.5535	0.9255	2.0669
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	7873.011	uM	2.75870	17.82940	-0.8049	-1.0000	0.5887	0.5802	0.9533	2.0810
MCF12A	NM	Basal B	Oxamflatin	HDAC	HDAC	12365.147	uM	2.23970	7.49230	-0.8632	-1.0000	0.9098	0.3651	0.9803	1.8376
MCF12A	NM	Basal B	Oxamflatin	HDAC	HDAC	10817.147	uM	2.26790	3.41440	-0.8823	-0.9018	2.5197	0.4431	0.9981	1.5041
MCF12A	NM	Basal B	PD 98059	MEK	MAPK	12365.152	uM	inf	59.37710	0.8928	0.6554	4.6295	-0.0014	0.7682	2.1145
MCF12A	NM	Basal B	PD 98059	MEK	MAPK	10817.152	uM	inf	9.33350	0.7524	0.7016	0.9343	0.0554	0.9109	1.4414
MCF12A	NM	Basal B	PD173074	FGFR1/3	RTK	7490.093	uM	23.21920	38.67090	0.1889	-0.9098	2.0321	0.0765	0.9852	2.3707
MCF12A	NM	Basal B	PD184352	MEK	MAPK	10817.155	uM	8.38830	73.96110	0.1203	-1.0000	0.5047	0.1828	0.8989	1.6045
MCF12A	NM	Basal B	PD184352	MEK	MAPK	10817.155	uM	8.38830	73.96110	0.1203	-1.0000	0.5047	0.1828	0.8989	1.6045

|<
<<
Previous
Page 209 of 370
Next
>>
>
5201 to 5225 of 9248 records
per page:

HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset (ID:20269)