Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7442.074 | 0.9809 | 0.9531 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7442.074 | 0.9936 | 0.9843 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7442.074 | 0.9473 | 0.8713 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7442.074 | 0.6056 | 0.0803 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7442.074 | 0.2832 | -0.5752 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7443.074 | 0.9688 | 0.9290 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7443.074 | 0.9720 | 0.9361 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7443.074 | 1.0032 | 1.0073 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7443.074 | 0.9801 | 0.9546 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7443.074 | 0.9766 | 0.9467 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7443.074 | 0.9627 | 0.9149 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7443.074 | 0.9093 | 0.7941 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7443.074 | 0.7000 | 0.3306 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7443.074 | 0.4963 | -0.1016 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7444.074 | 0.9915 | 0.9776 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7444.074 | 1.0196 | 1.0518 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7444.074 | 1.0047 | 1.0125 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7444.074 | 1.0420 | 1.1112 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7444.074 | 0.9989 | 0.9971 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7444.074 | 0.9921 | 0.9792 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7444.074 | 0.8863 | 0.7065 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7444.074 | 0.5719 | -0.0410 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7444.074 | 0.3230 | -0.5476 | 0.7602 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7447.074 | 0.9691 | 0.9597 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7447.074 | 0.9892 | 0.9860 | 1.5411 |