Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7437.074 | 1.0325 | 1.1781 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7437.074 | 0.9440 | 0.7148 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7437.074 | 0.7447 | -0.0892 | 0.3747 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7440.074 | 0.9614 | 0.8419 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7440.074 | 0.9730 | 0.8885 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7440.074 | 0.9434 | 0.7703 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7440.074 | 0.9402 | 0.7578 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7440.074 | 0.9619 | 0.8440 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7440.074 | 0.9999 | 0.9995 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7440.074 | 0.9492 | 0.7933 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7440.074 | 0.8589 | 0.4548 | 0.4778 | |
| HCC1419 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7440.074 | 0.7320 | 0.0410 | 0.4778 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7441.074 | 0.9707 | 0.9300 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7441.074 | 0.9896 | 0.9751 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7441.074 | 0.9506 | 0.8821 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7441.074 | 0.9924 | 0.9819 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7441.074 | 0.9165 | 0.8015 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7441.074 | 0.9490 | 0.8784 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7441.074 | 0.8985 | 0.7590 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7441.074 | 0.6094 | 0.1042 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7441.074 | 0.4375 | -0.2579 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7442.074 | 0.9989 | 0.9974 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7442.074 | 1.0214 | 1.0528 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7442.074 | 1.0019 | 1.0047 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7442.074 | 1.0187 | 1.0459 | 0.8143 |