Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.00213 | uM | 10875.149 | 1.0174 | 1.0466 | 0.7469 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0107 | uM | 10875.149 | 0.9793 | 0.9447 | 0.7469 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0533 | uM | 10875.149 | 0.9656 | 0.9084 | 0.7469 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.267 | uM | 10875.149 | 0.9475 | 0.8607 | 0.7469 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 1.33 | uM | 10875.149 | 0.9488 | 0.8640 | 0.7469 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 6.67 | uM | 10875.149 | 0.9169 | 0.7807 | 0.7469 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 33.3 | uM | 10875.149 | 0.6252 | 0.0664 | 0.7469 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.000256 | uM | 12428.166 | 1.0337 | 1.0822 | 0.8223 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.00128 | uM | 12428.166 | 1.0315 | 1.0768 | 0.8223 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0064 | uM | 12428.166 | 0.9791 | 0.9492 | 0.8223 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.032 | uM | 12428.166 | 1.0176 | 1.0430 | 0.8223 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.16 | uM | 12428.166 | 0.9309 | 0.8332 | 0.8223 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.8 | uM | 12428.166 | 1.0232 | 1.0566 | 0.8223 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 4 | uM | 12428.166 | 0.9497 | 0.8784 | 0.8223 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 20 | uM | 12428.166 | 0.8109 | 0.5501 | 0.8223 | |
SUM1315MO2 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 100 | uM | 12428.166 | 0.6337 | 0.1484 | 0.8223 | |
SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0000853 | uM | 10819.149 | 0.9589 | 0.9595 | 2.0505 | |
SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.000427 | uM | 10819.149 | 0.9549 | 0.9555 | 2.0505 | |
SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.00213 | uM | 10819.149 | 0.9571 | 0.9577 | 2.0505 | |
SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0107 | uM | 10819.149 | 0.9998 | 0.9998 | 2.0505 | |
SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0533 | uM | 10819.149 | 0.9507 | 0.9513 | 2.0505 | |
SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.267 | uM | 10819.149 | 0.9680 | 0.9685 | 2.0505 | |
SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 1.33 | uM | 10819.149 | 0.9437 | 0.9442 | 2.0505 | |
SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 6.67 | uM | 10819.149 | 0.8222 | 0.8179 | 2.0505 | |
SUM149PT | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 33.3 | uM | 10819.149 | 0.4109 | 0.2962 | 2.0505 |