Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.00213
uM
10875.149
1.0174 1.0466 0.7469
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.0107
uM
10875.149
0.9793 0.9447 0.7469
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.0533
uM
10875.149
0.9656 0.9084 0.7469
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.267
uM
10875.149
0.9475 0.8607 0.7469
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
1.33
uM
10875.149
0.9488 0.8640 0.7469
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
6.67
uM
10875.149
0.9169 0.7807 0.7469
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
33.3
uM
10875.149
0.6252 0.0664 0.7469
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.000256
uM
12428.166
1.0337 1.0822 0.8223
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.00128
uM
12428.166
1.0315 1.0768 0.8223
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.0064
uM
12428.166
0.9791 0.9492 0.8223
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.032
uM
12428.166
1.0176 1.0430 0.8223
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.16
uM
12428.166
0.9309 0.8332 0.8223
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.8
uM
12428.166
1.0232 1.0566 0.8223
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
4
uM
12428.166
0.9497 0.8784 0.8223
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
20
uM
12428.166
0.8109 0.5501 0.8223
SUM1315MO2
TNBC
Basal B
FR180204
ERK1/2
MAPK
100
uM
12428.166
0.6337 0.1484 0.8223
SUM149PT
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.0000853
uM
10819.149
0.9589 0.9595 2.0505
SUM149PT
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.000427
uM
10819.149
0.9549 0.9555 2.0505
SUM149PT
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.00213
uM
10819.149
0.9571 0.9577 2.0505
SUM149PT
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.0107
uM
10819.149
0.9998 0.9998 2.0505
SUM149PT
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.0533
uM
10819.149
0.9507 0.9513 2.0505
SUM149PT
TNBC
Basal B
FR180204
ERK1/2
MAPK
0.267
uM
10819.149
0.9680 0.9685 2.0505
SUM149PT
TNBC
Basal B
FR180204
ERK1/2
MAPK
1.33
uM
10819.149
0.9437 0.9442 2.0505
SUM149PT
TNBC
Basal B
FR180204
ERK1/2
MAPK
6.67
uM
10819.149
0.8222 0.8179 2.0505
SUM149PT
TNBC
Basal B
FR180204
ERK1/2
MAPK
33.3
uM
10819.149
0.4109 0.2962 2.0505