Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 13.3 | uM | 7467.091 | 0.9238 | 0.8816 | 1.2996 | |
| HCC3153 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 66.7 | uM | 7467.091 | 0.6876 | 0.4992 | 1.2996 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7468.091 | 1.0416 | 1.0557 | 1.4852 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7468.091 | 0.9908 | 0.9876 | 1.4852 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7468.091 | 1.0490 | 1.0654 | 1.4852 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7468.091 | 1.0042 | 1.0056 | 1.4852 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.107 | uM | 7468.091 | 1.0031 | 1.0041 | 1.4852 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.533 | uM | 7468.091 | 0.9349 | 0.9114 | 1.4852 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 2.67 | uM | 7468.091 | 0.9997 | 0.9996 | 1.4852 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 13.3 | uM | 7468.091 | 0.9242 | 0.8966 | 1.4852 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 66.7 | uM | 7468.091 | 0.8091 | 0.7342 | 1.4852 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7469.09 | 1.0679 | 1.0673 | 1.9867 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7469.09 | 1.0496 | 1.0493 | 1.9867 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7469.09 | 1.1202 | 1.1176 | 1.9867 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7469.09 | 1.0086 | 1.0086 | 1.9867 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.107 | uM | 7469.09 | 1.0035 | 1.0036 | 1.9867 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.533 | uM | 7469.09 | 0.9895 | 0.9894 | 1.9867 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 2.67 | uM | 7469.09 | 1.0401 | 1.0400 | 1.9867 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 13.3 | uM | 7469.09 | 1.0093 | 1.0093 | 1.9867 | |
| HCC38 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 66.7 | uM | 7469.09 | 0.8744 | 0.8694 | 1.9867 | |
| HCC70 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7470.091 | 1.0080 | 1.0163 | 0.9773 | |
| HCC70 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7470.091 | 1.0278 | 1.0570 | 0.9773 | |
| HCC70 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7470.091 | 1.0069 | 1.0142 | 0.9773 | |
| HCC70 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7470.091 | 0.9479 | 0.8935 | 0.9773 | |
| HCC70 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.107 | uM | 7470.091 | 0.8664 | 0.7270 | 0.9773 |