Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7430.091 | 1.0469 | 1.0525 | 1.7667 | |
| HCC1143 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7430.091 | 1.1125 | 1.1244 | 1.7667 | |
| HCC1143 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7430.091 | 1.0842 | 1.0937 | 1.7667 | |
| HCC1143 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7430.091 | 1.0750 | 1.0835 | 1.7667 | |
| HCC1143 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.107 | uM | 7430.091 | 0.9850 | 0.9829 | 1.7667 | |
| HCC1143 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.533 | uM | 7430.091 | 0.9081 | 0.8938 | 1.7667 | |
| HCC1143 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 2.67 | uM | 7430.091 | 0.9426 | 0.9341 | 1.7667 | |
| HCC1143 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 13.3 | uM | 7430.091 | 0.7758 | 0.7323 | 1.7667 | |
| HCC1143 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 66.7 | uM | 7430.091 | 0.6310 | 0.5411 | 1.7667 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7431.092 | 0.9626 | 0.9498 | 1.5006 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7431.092 | 0.9420 | 0.9220 | 1.5006 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7431.092 | 0.9682 | 0.9574 | 1.5006 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7431.092 | 0.9627 | 0.9500 | 1.5006 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7431.092 | 0.9230 | 0.8961 | 1.5006 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.267 | uM | 7431.092 | 0.8082 | 0.7354 | 1.5006 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 1.33 | uM | 7431.092 | 0.7788 | 0.6931 | 1.5006 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 6.67 | uM | 7431.092 | 0.7084 | 0.5895 | 1.5006 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 33.3 | uM | 7431.092 | 0.5490 | 0.3411 | 1.5006 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7432.091 | 0.9608 | 0.9232 | 1.0227 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7432.091 | 0.9058 | 0.8156 | 1.0227 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7432.091 | 0.9879 | 0.9764 | 1.0227 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7432.091 | 0.9753 | 0.9516 | 1.0227 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.107 | uM | 7432.091 | 0.8864 | 0.7776 | 1.0227 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 0.533 | uM | 7432.091 | 0.8906 | 0.7857 | 1.0227 | |
| HCC1187 | TNBC | Basal A | Erlotinib | EGFR | ErbB | 2.67 | uM | 7432.091 | 0.8000 | 0.6080 | 1.0227 |