Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7918.017 | 1.0682 | 1.0419 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7918.017 | 0.7378 | 0.8178 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7918.017 | 0.2707 | 0.3267 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7918.017 | 0.0705 | -0.1308 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7918.017 | 0.0596 | -0.1755 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7918.017 | 0.0241 | -0.3793 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7918.017 | 0.4429 | 0.5485 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7919.017 | 1.0503 | 1.0260 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7919.017 | 1.0227 | 1.0119 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7919.017 | 1.0251 | 1.0131 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7919.017 | 0.9455 | 0.9707 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7919.017 | 0.1606 | 0.2354 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7919.017 | 0.0168 | -0.3190 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7919.017 | 0.0440 | -0.1219 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7919.017 | 0.0105 | -0.3976 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7919.017 | 0.0008 | -0.6913 | 3.7958 | |
| SUM185PE | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7921.017 | 1.0187 | 1.0468 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7921.017 | 1.0475 | 1.1191 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7921.017 | 1.0246 | 1.0616 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7921.017 | 0.9550 | 0.8885 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7921.017 | 0.8839 | 0.7146 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7921.017 | 0.2934 | -0.5667 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7921.017 | 0.3139 | -0.5287 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7921.017 | 0.1569 | -0.8014 | 0.8018 | |
| SUM185PE | TNBC | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7921.017 | 0.0031 | -0.9985 | 0.8018 |