Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7870.017 | 0.6737 | 0.6487 | 2.0447 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7870.017 | 0.0071 | -0.8225 | 2.0447 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7870.017 | 0.0066 | -0.8288 | 2.0447 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7870.017 | 0.0070 | -0.8234 | 2.0447 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7870.017 | 0.0008 | -0.9394 | 2.0447 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9551.017 | 1.0602 | 1.0457 | 2.5886 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9551.017 | 1.0276 | 1.0211 | 2.5886 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 9551.017 | 1.0919 | 1.0691 | 2.5886 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9551.017 | 0.7375 | 0.7780 | 2.5886 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 9551.017 | 0.5388 | 0.5749 | 2.5886 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 9551.017 | 0.0118 | -0.6397 | 2.5886 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 9551.017 | 0.0085 | -0.6835 | 2.5886 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 9551.017 | 0.0085 | -0.6829 | 2.5886 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 9551.017 | 0.0066 | -0.7121 | 2.5886 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7872.017 | 1.0115 | 1.0151 | 1.5155 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7872.017 | 0.9856 | 0.9809 | 1.5155 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 0.011 | uM | 7872.017 | 1.0289 | 1.0379 | 1.5155 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7872.017 | 0.9892 | 0.9858 | 1.5155 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 0.276 | uM | 7872.017 | 0.9251 | 0.8999 | 1.5155 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 1.38 | uM | 7872.017 | 0.6792 | 0.5494 | 1.5155 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 6.9 | uM | 7872.017 | 1.0445 | 1.0583 | 1.5155 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 34.5 | uM | 7872.017 | 1.0396 | 1.0520 | 1.5155 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 172 | uM | 7872.017 | 0.9669 | 0.9560 | 1.5155 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9566.017 | 1.0975 | 1.0875 | 2.1734 | |
| MCF 10F | NM | - | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9566.017 | 1.0313 | 1.0285 | 2.1734 |