Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7865.017 | 0.1661 | -0.2171 | 1.9138 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7865.017 | 0.2690 | 0.0071 | 1.9138 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7865.017 | 0.0021 | -0.9199 | 1.9138 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9536.017 | 1.0094 | 1.0129 | 1.4526 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9536.017 | 0.9891 | 0.9850 | 1.4526 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 9536.017 | 1.0010 | 1.0014 | 1.4526 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9536.017 | 1.0000 | 1.0000 | 1.4526 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 9536.017 | 0.7493 | 0.6396 | 1.4526 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 9536.017 | 0.1117 | -0.5577 | 1.4526 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 9536.017 | 0.1974 | -0.3454 | 1.4526 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 9536.017 | 0.2774 | -0.1727 | 1.4526 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 9536.017 | 0.0033 | -0.9612 | 1.4526 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7867.017 | 0.9724 | 0.9779 | 2.5255 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7867.017 | 1.0166 | 1.0131 | 2.5255 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7867.017 | 0.9283 | 0.9419 | 2.5255 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7867.017 | 0.7162 | 0.7524 | 2.5255 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7867.017 | 0.5446 | 0.5723 | 2.5255 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7867.017 | 0.0060 | -0.7354 | 2.5255 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7867.017 | 0.0075 | -0.7117 | 2.5255 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7867.017 | 0.0070 | -0.7195 | 2.5255 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7867.017 | 0.0032 | -0.7942 | 2.5255 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7870.017 | 1.0376 | 1.0365 | 2.0447 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7870.017 | 1.0131 | 1.0128 | 2.0447 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7870.017 | 0.9996 | 0.9996 | 2.0447 | |
| MCF 10A | NM | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7870.017 | 0.8925 | 0.8918 | 2.0447 |