Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MCF12A	NM	Basal B	Everolimus	MTOR	MTOR	0.107	uM	12365.164	0.8128	0.8099	2.0756
MCF12A	NM	Basal B	Everolimus	MTOR	MTOR	0.533	uM	12365.164	0.7842	0.7790	2.0756
MCF12A	NM	Basal B	Everolimus	MTOR	MTOR	2.67	uM	12365.164	0.7459	0.7366	2.0756
MCF12A	NM	Basal B	Everolimus	MTOR	MTOR	13.3	uM	12365.164	0.6724	0.6519	2.0756
MCF12A	NM	Basal B	Everolimus	MTOR	MTOR	66.7	uM	12365.164	0.0115	-0.7678	2.0756
MCF7	HR+	Luminal	Everolimus	MTOR	MTOR	0.000171	uM	10997.156	1.0601	1.1153	1.0411
MCF7	HR+	Luminal	Everolimus	MTOR	MTOR	0.000853	uM	10997.156	1.1741	1.3334	1.0411
MCF7	HR+	Luminal	Everolimus	MTOR	MTOR	0.00427	uM	10997.156	1.0297	1.0571	1.0411
MCF7	HR+	Luminal	Everolimus	MTOR	MTOR	0.0213	uM	10997.156	1.0648	1.1244	1.0411
MCF7	HR+	Luminal	Everolimus	MTOR	MTOR	0.107	uM	10997.156	0.6495	0.3213	1.0411
MCF7	HR+	Luminal	Everolimus	MTOR	MTOR	0.533	uM	10997.156	0.6507	0.3236	1.0411
MCF7	HR+	Luminal	Everolimus	MTOR	MTOR	2.67	uM	10997.156	0.6031	0.2305	1.0411
MCF7	HR+	Luminal	Everolimus	MTOR	MTOR	13.3	uM	10997.156	0.5090	0.0455	1.0411
MCF7	HR+	Luminal	Everolimus	MTOR	MTOR	66.7	uM	10997.156	0.2776	-0.4159	1.0411
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	0.000171	uM	10998.156	1.0570	1.1947	0.5969
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	0.000853	uM	10998.156	1.0589	1.2012	0.5969
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	0.00427	uM	10998.156	0.9638	0.8803	0.5969
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	0.0213	uM	10998.156	0.9081	0.7019	0.5969
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	0.107	uM	10998.156	0.6321	-0.0725	0.5969
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	0.533	uM	10998.156	0.6897	0.0733	0.5969
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	2.67	uM	10998.156	0.6579	-0.0084	0.5969
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	13.3	uM	10998.156	0.6246	-0.0910	0.5969
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	66.7	uM	10998.156	0.3725	-0.6176	0.5969
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	0.000171	uM	12206.164	0.9636	0.9260	0.9848
MDA-MB-134-VI	HR+	Luminal	Everolimus	MTOR	MTOR	0.000853	uM	12206.164	0.9442	0.8867	0.9848

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)