Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9095.049 | 0.9849 | 0.9730 | 1.1202 | |
| 184B5 | NM | Basal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9095.049 | 0.8801 | 0.7846 | 1.1202 | |
| 184B5 | NM | Basal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9095.049 | 0.6416 | 0.3458 | 1.1202 | |
| 184B5 | NM | Basal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9095.049 | 0.5083 | 0.0932 | 1.1202 | |
| 184B5 | NM | Basal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9095.049 | 0.4489 | -0.0216 | 1.1202 | |
| 184B5 | NM | Basal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9095.049 | 0.4278 | -0.0629 | 1.1202 | |
| 184B5 | NM | Basal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9095.049 | 0.3254 | -0.2658 | 1.1202 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 7791.016 | 1.1023 | 1.2542 | 0.8138 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 7791.016 | 1.1027 | 1.2553 | 0.8138 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 7791.016 | 1.0508 | 1.1256 | 0.8138 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 7791.016 | 1.0593 | 1.1467 | 0.8138 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 7791.016 | 0.9917 | 0.9796 | 0.8138 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 7791.016 | 0.9511 | 0.8804 | 0.8138 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 7791.016 | 0.8120 | 0.5484 | 0.8138 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 7791.016 | 0.7866 | 0.4891 | 0.8138 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 7791.016 | 0.4184 | -0.3145 | 0.8138 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0000853 | uM | 9118.019 | 0.9841 | 0.9702 | 1.0707 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.000427 | uM | 9118.019 | 1.0590 | 1.1099 | 1.0707 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.00213 | uM | 9118.019 | 0.9713 | 0.9464 | 1.0707 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0107 | uM | 9118.019 | 1.0078 | 1.0145 | 1.0707 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.0533 | uM | 9118.019 | 1.0250 | 1.0466 | 1.0707 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 0.267 | uM | 9118.019 | 0.9601 | 0.9254 | 1.0707 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 1.33 | uM | 9118.019 | 0.8815 | 0.7778 | 1.0707 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 6.67 | uM | 9118.019 | 0.8683 | 0.7529 | 1.0707 | |
| 600MPE | HR+ | Luminal | Gefitinib | EGFR | ErbB | 33.3 | uM | 9118.019 | 0.4410 | -0.0690 | 1.0707 |